943321-89-9 Usage
Uses
Used in Pharmaceutical Industry:
(5-BROMO-THIOPHEN-2-YL)-CARBAMIC ACID TERT-BUTYL ESTER is used as a reagent in organic synthesis for the development of new pharmaceutical compounds. Its unique chemical structure allows it to be a key intermediate in the creation of various medicinal agents, contributing to the advancement of drug discovery and therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, (5-BROMO-THIOPHEN-2-YL)-CARBAMIC ACID TERT-BUTYL ESTER is utilized as an intermediate in the synthesis of agrochemicals. Its role in this industry is crucial for the development of new pesticides and other agricultural chemicals that can improve crop protection and yield.
Used in Dye and Pigment Production:
(5-BROMO-THIOPHEN-2-YL)-CARBAMIC ACID TERT-BUTYL ESTER is used as a building block in the production of dyes and pigments. Its chemical properties make it suitable for creating a variety of colorants used in different industries, including textiles, plastics, and printing inks.
Used in Material Science Research:
(5-BROMO-THIOPHEN-2-YL)-CARBAMIC ACID TERT-BUTYL ESTER is also used as a research tool in material science. It serves as a component in the development of new materials with unique properties, such as high-performance polymers and advanced composites, which can be applied in various industrial and technological fields.
Due to its potential biological and industrial applications, it is imperative to handle (5-BROMO-THIOPHEN-2-YL)-CARBAMIC ACID TERT-BUTYL ESTER with care and in accordance with safety guidelines to ensure the safety of both individuals and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 943321-89-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,3,3,2 and 1 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 943321-89:
(8*9)+(7*4)+(6*3)+(5*3)+(4*2)+(3*1)+(2*8)+(1*9)=169
169 % 10 = 9
So 943321-89-9 is a valid CAS Registry Number.
943321-89-9Relevant academic research and scientific papers
Discovery of 5-pyrrolopyridinyl-2-thiophenecarboxamides as potent AKT kinase inhibitors
Seefeld, Mark A.,Rouse, Meagan B.,McNulty, Kenneth C.,Sun, Lihui,Wang, Jizhou,Yamashita, Dennis S.,Luengo, Juan I.,Zhang, ShuYun,Minthorn, Elisabeth A.,Concha, Nestor O.,Heerding, Dirk A.
scheme or table, p. 2244 - 2248 (2009/12/07)
A pyrrolopyridinyl thiophene carboxamide 7 was discovered as a tractable starting point for a lead optimization effort in an AKT kinase inhibition program. SAR studies aided by a co-crystal structure of 7 in AKT2 led to the identification of AKT inhibitor
INHIBITORS OF Akt ACTIVITY
-
Page/Page column 90, (2010/11/27)
Invented are novel thiophene compounds, the use of such compounds as inhibitors of protein kinase B activity and in the treatment of cancer and arthritis.
Novel thienopyrrole glycogen phosphorylase inhibitors: Synthesis, in vitro SAR and crystallographic studies
Whittamore, Paul R.O.,Addie, Matthew S.,Bennett, Stuart N.L.,Birch, Alan M.,Butters, Michael,Godfrey, Linda,Kenny, Peter W.,Morley, Andrew D.,Murray, Paul M.,Oikonomakos, Nikos G.,Otterbein, Ludovic R.,Pannifer, Andrew D.,Parker, Jeremy S.,Readman, Kristy,Siedlecki, Pawel S.,Schofield, Paul,Stocker, Andy,Taylor, Melvyn J.,Townsend, Linda A.,Whalley, David P.,Whitehouse, Jennifer
, p. 5567 - 5571 (2007/10/03)
Two series of novel thienopyrrole inhibitors of recombinant human liver glycogen phosphorylase a (GPa) which are effective in reducing glucose output from rat hepatocytes are described. Representative compounds have been shown to bind at the dimer interface site of the rabbit muscle enzyme by X-ray crystallography.
