68241-78-1Relevant articles and documents
Small-scale procedure for acid-catalyzed ketal formation
Wright, Austin C.,Du, Yun Emily,Stoltz, Brian M.
, p. 11258 - 11260 (2019)
A modified procedure for dehydrative ketal protections is disclosed, which serves as an alternative to the classic Dean-Stark protocol. Studies show that this new procedure can outperform the Dean-Stark apparatus on small scales and thus serves as a complementary approach to effect dehydrative ketalizations. A detailed procedure for this apparatus is presented.
Enantioselective construction of the tricyclic core of curcusones A-D: Via a cross-electrophile coupling approach
Wright, Austin C.,Stoltz, Brian M.
, p. 10562 - 10565 (2019/12/02)
Herein we report our recent progress toward the enantioselective total synthesis of the diterpenoid natural products curcusones A-D by means of complementary Stetter annulation or ring-closing metathesis (RCM) disconnections. Using the latter approach, we
Synthesis and stereochemical confirmation of the secoiridoid glucosides nudiflosides D and A
Hanessian, Stephen,Mainetti, Emily,Lecomte, Fabien
, p. 4047 - 4049 (2007/10/03)
We describe herein an efficient access to the highly substituted cyclopentane unit present in the Nudifloside secoiridoid family via crotyl phosphonamide anion mediated conjugate addition to cyclopentenone.