68254-10-4

Basic information

• Product Name: 1-(4-chlorophenyl)-6-methyl-4-oxo-pyridazine-3-carboxylate
• Synonyms: 1-(4-chlorophenyl)-6-methyl-4-oxo-pyridazine-3-carboxylate;Fenridazon [iso];1-(4-chlorophenyl)-6-Methyl-4-oxo-1,4-dihydropyridazine-3-carboxylate;1-(4-Chlorophenyl)-1,4-dihydro-6-methyl-4-oxo-3-pyridazinecarboxylic acid
• CAS NO: 68254-10-4
• Molecular Formula: C₁₂H₉ClN₂O₃
• Molecular Weight: 264.66
• Mol File: 68254-10-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 234.3-235.1℃ (ethanol )
• Boiling Point: 453.4°C at 760 mmHg
• Flash Point: 228°C
• Appearance: /
• Density: 1.43±0.1 g/cm3(Predicted)
• Vapor Pressure: 5.21E-09mmHg at 25°C
• PKA: 0.17±0.20(Predicted)
• CAS DataBase Reference: 1-(4-chlorophenyl)-6-methyl-4-oxo-pyridazine-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-chlorophenyl)-6-methyl-4-oxo-pyridazine-3-carboxylate(68254-10-4)
• EPA Substance Registry System: 1-(4-chlorophenyl)-6-methyl-4-oxo-pyridazine-3-carboxylate(68254-10-4)

Safety Data

• Hazardous Substances Data: 68254-10-4(Hazardous Substances Data)

Usage

General Description

1-(4-chlorophenyl)-6-methyl-4-oxo-pyridazine-3-carboxylate is a chemical compound with the molecular formula C13H9ClN2O3. It is a pyridazine derivative, which is a class of organic compounds containing a pyridazine ring. 1-(4-chlorophenyl)-6-methyl-4-oxo-pyridazine-3-carboxylate is characterized by the presence of a 4-chlorophenyl group, a methyl group, and a carboxylate group attached to the pyridazine ring. It is often used as a building block in the synthesis of pharmaceuticals and agrochemicals due to its versatile reactivity and potential biological activity. 1-(4-chlorophenyl)-6-methyl-4-oxo-pyridazine-3-carboxylate may also have applications in material science and organic chemistry. It is important to handle and use this compound with proper safety precautions due to its potential hazards.

InChI:InChI=1/C12H9ClN2O3/c1-7-6-10(16)11(12(17)18)14-15(7)9-4-2-8(13)3-5-9/h2-6H,1H3,(H,17,18)/p-1

Upstream product

• 771-03-9 3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one 
• 675-10-5 4-hydroxy-6-methyl-2-pyron 
• 78242-72-5 C₁₂H₉ClN₂O₃ 
• 106-47-8 4-chloro-aniline 
• 541-98-0 6-methyl-pyran-2,4-dione 
• 17333-85-6 4-chlorophenyldiazonium salt 

Downstream Products

• 83499-20-1 Dimethyl 1-(4-Chlorophenyl)-1,4-dihydro-4-oxo-6-methylpyridazine-3-carboxamide 
• 68253-83-8 methyl 1-(4-chlorophenyl)-1,4-dihydro-4-oxo-6-methyl pyridazine-3-carboxylate 
• 80601-23-6 Benzyl 1-(4-Chlorophenyl)-1,4-dihydro-4-oxo-6-methyl pyridazine-3-carboxylate 
• 83499-25-6 3-Bromopropyl 1-(4-Chlorophenyl)-1,4-dihydro-4-oxo-6-methyl pyridazine-3-carboxylate 

Relevant articles and documents

The Generation of a Library of Bromodomain-Containing Protein Modulators Expedited by Continuous Flow Synthesis

A continuous flow process delivering key building blocks for a series of BCP modulator libraries is reported. A dynamically mixed flow reactor emerged as a pivotal technology in both synthesis and isolation phases enabling the processing of slurries and suspensions while maintaining high productivity and reliability. Accordingly, the synthesis of common intermediates in flow were employed to further build a pyridazone-based library (36 compounds) aimed at improving lead compound potency and selectivity while further enabling structure-activity relationship studies of a new BCP modulator family.

Hybridization of sunflowers and safflowers

A method of inducing male sterility in a dicotyledonous plant which comprises treating the plant prior to, during or post meiosis with an amount of a substituted 4-oxo-1-phenyl-1,4-dihydropyridazine, which is effective to produce male sterility in the plant.