68266-57-9

Usage

Class

Carboxylic acids

Molecular weight

296.77 g/mol

Potential role

Intermediate in the synthesis of pharmaceutical products and organic compounds

Use

Building block in the production of various drugs

Unique structure

Contains a chlorine atom, cyclopentylmethyl group, and indene ring

Functional groups

Carboxylic acid group (COOH) and Chlorine atom (Cl)

Potential biological activities

Not specified, requires further research and development

InChI:InChI=1/C16H19ClO2/c17-15-9-14-11(5-6-13(14)16(18)19)8-12(15)7-10-3-1-2-4-10/h8-10,13H,1-7H2,(H,18,19)

Upstream product

• 112-27-6 2,2'-[1,2-ethanediylbis(oxy)]bisethanol 
• 7333-52-0 cyclopenthyltriphenylphosphonium bromide 
• 68266-63-7 6-chloro-5-formylindan-1-carboxylic acid 
• 52651-15-7 6-chloro-indane-1-carboxylic acid 
• 70780-14-2 6-chloro-5-(cyclopentylidenemethyl)indan-1-carboxylic acid 

Relevant academic research and scientific papers

Nonsteroidal Antiinflammatory Agents. 14. Synthesis and Pharmacological Profile of 6-Chloro-5-(cyclopentylmethyl)indan-1-carboxylic Acid

The preparation of 6-chloro-5-(cyclopentylmethyl)indan-1-carboxylic acid is described.This acid has good antiinlammatory and analgesic activities without producing irritation in the gastrointestinal tract up to the highest tested dose.

Novel phenylacetic acid derivatives

Phenylacetic acid derivatives of the formula STR1 wherein n is an integer of 2 to 5; STR2 R1 is hydrogen, halogen, trifluoromethyl, nitro or amino; R2 and R3 each independently is hydrogen or lower alkyl; or together form an ethylene group; X1 represents two hydrogen atoms or an oxo group; and Y1 is cyano, hydroxyamidocarbonyl, carbamoyl, 5-tetrazolyl or carboxyl; and for derivatives wherein Y is carboxyl, salts thereof with physiologically compatible bases, esters thereof from physiologically acceptable alcohols and amides thereof from physiologically acceptable amines have valuable pharmacological activity, e.g., as antiinflammatory agents.

Derivatives of antiphlogistically effective carboxylic acids, their preparation and medicinal use

Compounds of Formula I STR1 wherein R1 is the residue of an antiphlogistically effective carboxylic acid of the formula R1 COOH, n is an integer 1, 2, or 3, and X is oxygen, sulfur, or optionally alkylated nitrogen have valuable antiinflammatory activity.