682746-71-0Relevant academic research and scientific papers
Synthesis and Enzymatic Kinetic Resolution of α,α -Disubstituted Cyclic Hydroxy Nitriles
Levy, Laura M.,Gotor, Vicente
, p. 2601 - 2602 (2007/10/03)
Herein, we describe the diastereoselective synthesis of five- and six-membered α,α-disubstituted cyclic β-hydroxy nitriles and their resolution via enzymatic transesterification. By this method, all possible stereoisomers were obtained in enantiopure form and high yield.
