682774-64-7

Basic information

• Product Name: Cyclohexanol, 2-ethynyl-1-methyl-4-(phenylmethoxy)-, (1R,2S,4S)-
• CAS NO: 682774-64-7
• Molecular Formula: C16H20O2
• Molecular Weight: 244.334
• Mol File: 682774-64-7.mol

Chemical Properties

• CAS DataBase Reference: Cyclohexanol, 2-ethynyl-1-methyl-4-(phenylmethoxy)-, (1R,2S,4S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanol, 2-ethynyl-1-methyl-4-(phenylmethoxy)-, (1R,2S,4S)-(682774-64-7)
• EPA Substance Registry System: Cyclohexanol, 2-ethynyl-1-methyl-4-(phenylmethoxy)-, (1R,2S,4S)-(682774-64-7)

Safety Data

• Hazardous Substances Data: 682774-64-7(Hazardous Substances Data)

Upstream product

• 203719-53-3 (-)-limonene oxide 
• 203508-62-7 1-(3S)-(6-methyl-7-oxabicyclo[4.1.0]heptan-3-yl)ethanone 
• 5989-54-8 (-)-(S)-limonene 
• 70277-75-7 lithium acetylide 

Downstream Products

• 682774-68-1 (1S,2S,4R,6R)-4-Benzyloxy-2-ethynyl-1-methyl-7-oxa-bicyclo[4.1.0]heptane 
• 682774-67-0 (3R,4S,6S)-6-Benzyloxy-4-ethynyl-1-oxa-spiro[2.5]octane 

Relevant articles and documents

Vitamin D: A concise synthesis of the C19 hydroxylated enyne A-ring, an interesting precursor for the preparation of C19 substituted vitamin D analogues

A new C19 hydroxylated enyne 15, as potential A-ring building block of vitamin D analogues, was synthesized in enantiomerically pure form in nine steps from (-)-(S)-limonene. This short synthesis involved ozonolyzis of 1,2-limonene oxide followed by a Criegee rearrangement, epoxide trans diaxial ring opening by lithium acetylide, elimination, epoxidation and syn β-elimination of the resulting homopropargylic oxirane.