682804-40-6Relevant articles and documents
Regiospecific chlorination of (S)-β-tyrosyl-S-carrier protein catalyzed by SgcC3 in the biosynthesis of the enediyne antitumor antibiotic C-1027
Lin, Shuangjun,Van Lanen, Steven G.,Shen, Ben
, p. 12432 - 12438 (2007)
C-1027 is a potent antitumor antibiotic composed of an apo-protein and a reactive enediyne chromophore. The chromophore consists of four different chemical subunits including an (S)-3-chloro-4,5-dihydroxy-β-phenylalanine moiety, the biosynthesis of which