682805-12-5 Usage
Uses
Used in Laboratory Research:
2-Chloro-5-(trifluoromethyl)cinnamic acid is used as a research compound for studying its chemical properties and potential applications in various fields. Its unique structure and stability make it a valuable subject for scientific investigation.
Used in Industrial Applications:
2-Chloro-5-(trifluoromethyl)cinnamic acid is used as an intermediate in the synthesis of various chemical products, such as pharmaceuticals, agrochemicals, and other specialty chemicals. Its stability and reactivity contribute to the development of new compounds with desired properties.
Used in Pharmaceutical Industry:
2-Chloro-5-(trifluoromethyl)cinnamic acid is used as a building block in the development of new drugs. Its unique structure and reactivity can be exploited to create novel pharmaceutical compounds with potential therapeutic applications.
Used in Agrochemical Industry:
2-Chloro-5-(trifluoromethyl)cinnamic acid is used as a starting material in the synthesis of agrochemicals, such as pesticides and herbicides. Its properties can be utilized to develop new compounds with improved efficacy and reduced environmental impact.
Used in Specialty Chemicals:
2-Chloro-5-(trifluoromethyl)cinnamic acid is used as a key component in the production of specialty chemicals, such as dyes, fragrances, and flavorings. Its unique properties can be harnessed to create new compounds with specific characteristics for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 682805-12-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,8,2,8,0 and 5 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 682805-12:
(8*6)+(7*8)+(6*2)+(5*8)+(4*0)+(3*5)+(2*1)+(1*2)=175
175 % 10 = 5
So 682805-12-5 is a valid CAS Registry Number.
682805-12-5Relevant academic research and scientific papers
Design, synthesis and cytotoxic evaluation of novel imatinib amide derivatives that target Abl kinase
Yao, Ri-Sheng,Guan, Qiu-Xiang,Lu, Xiao-Qin,Ruan, Ban-Feng
, p. 20 - 28 (2015/03/31)
Novel imatinib amide derivatives (a1-28, b1-9) were synthesized and evaluated for their biological activities. All compounds were characterized by 1H NMR, MS and elemental analysis. Among all the derivatives, compounds a4, a10, a21, b1 and b2 displayed the most significant ability of inhibiting K562 cell proliferation with the IC50 values of 0.67, 0.66, 0.65, 0.59 and 0.62 μM, respectively, indicating that these compounds were potent inhibitors of Bcr-Abl in leukemic K562 cells, comparable to the reference compound imatinib. Molecular docking study was performed to position compounds a21 and b1 into the active site of Abl to determine the probable binding modes
