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1-(4-nitrophenyl)-1H-pyrazole-4-carboxylic acid is a chemical compound characterized by the molecular formula C11H7N3O4. It is a derivative of pyrazole-4-carboxylic acid, featuring a nitrophenyl group attached to the 1-position. 1-(4-nitrophenyl)-1H-pyrazole-4-carboxylic acid is recognized for its potential pharmacological properties and has been the subject of research for its antitumor and anti-HIV activities. Furthermore, it has been explored as a possible inhibitor of enzymes that play a role in various disease processes, making it a significant and adaptable compound in the realms of chemical research and drug discovery.

68287-79-6

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68287-79-6 Usage

Uses

Used in Organic Synthesis:
1-(4-nitrophenyl)-1H-pyrazole-4-carboxylic acid is utilized as a building block in organic synthesis for the preparation of a wide range of biologically active compounds. Its unique structure and functional groups make it a valuable component in the creation of new molecules with potential applications in various fields.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-(4-nitrophenyl)-1H-pyrazole-4-carboxylic acid is used as a key component in the development of pharmaceuticals. Its incorporation into drug candidates can potentially enhance their efficacy and selectivity, contributing to the advancement of novel therapeutics.
Used in Antitumor Applications:
1-(4-nitrophenyl)-1H-pyrazole-4-carboxylic acid is employed as an antitumor agent, with studies indicating its potential to combat various types of cancer. Its specific mode of action and interaction with cellular targets are areas of ongoing research, with the aim of improving cancer treatment options.
Used in Anti-HIV Applications:
1-(4-nitrophenyl)-1H-pyrazole-4-carboxylic acid is also being investigated for its anti-HIV properties, as it may hold promise in the development of new antiviral drugs. Understanding its mechanism of action against the HIV virus could lead to the creation of more effective treatments for HIV and AIDS.
Used in Enzyme Inhibition:
1-(4-nitrophenyl)-1H-pyrazole-4-carboxylic acid has been studied for its potential as an inhibitor of key enzymes involved in disease processes. By targeting these enzymes, the compound may play a role in the development of new therapies for a variety of conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 68287-79-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,2,8 and 7 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 68287-79:
(7*6)+(6*8)+(5*2)+(4*8)+(3*7)+(2*7)+(1*9)=176
176 % 10 = 6
So 68287-79-6 is a valid CAS Registry Number.

68287-79-6Relevant academic research and scientific papers

Molecular docking and pharmacological/toxicological assessment of a new compound designed from celecoxib and paracetamol by molecular hybridization

da Silva, Daiany P. B.,Florentino, Iziara F.,da Silva, Dayane M.,Lino, Roberta C.,Cardoso, Carina S.,Moreira, Lorrane K. S.,Vasconcelos, Géssica A.,Vinhal, Daniela C.,Cardoso, Anna C. D.,Villavicencio, Bianca,Verli, Hugo,Vaz, Boniek G.,Li?o, Luciano M.,da Cunha, Luiz C.,Menegatti, Ricardo,Costa, Elson A.

, p. 1189 - 1206 (2018/07/31)

Nonsteroidal anti-inflammatory drugs are commonly used worldwide; however, they have several adverse effects, evidencing the need for the development of new, more effective and safe anti-inflammatory and analgesic drugs. This research aimed to design, syn

Synthesis and leishmanicidal activities of 1-(4-X-phenyl)-N′-[(4-Y- phenyl)methylene]-1H-pyrazole-4-carbohydrazides

Bernardino, Alice M.R.,Gomes, Adriana O.,Charret, Karen S.,Freitas, Antonio C.C.,Machado, Gerzia M.C.,Canto-Cavalheiro, Marilene M.,Leon, Leonor L.,Amaral, Veronica F.

, p. 80 - 87 (2007/10/03)

1H-pyrazole-4-carbohydrazides were synthesized and their leishmanicidal in vitro activities and cytotoxic effects were investigated. The drugs prototypes of these new compounds (ketoconazole, benznidazole, allopurinol and pentamidine) were also tested. It

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