70375-82-5Relevant academic research and scientific papers
Solvent-free and montmorillonite K10-catalyzed domino reactions for the synthesis of pyrazoles with alkynylester as a dual synthon
Annes, Sesuraj Babiola,Ramesh, Subburethinam,Saritha, Rajendhiran,Shankar, Bhaskaran,Subramanian, Saravanan
supporting information, p. 2388 - 2393 (2020/05/13)
A highly regioselective, solvent-free and montmorillonite K10 clay-catalyzed domino process with an unprecedented ring-closing C-C bond-formation reaction is described for the synthesis of a new class of 1,3,4-trisubstituted and 1,4-disubstituted pyrazole
Molecular docking and pharmacological/toxicological assessment of a new compound designed from celecoxib and paracetamol by molecular hybridization
da Silva, Daiany P. B.,Florentino, Iziara F.,da Silva, Dayane M.,Lino, Roberta C.,Cardoso, Carina S.,Moreira, Lorrane K. S.,Vasconcelos, Géssica A.,Vinhal, Daniela C.,Cardoso, Anna C. D.,Villavicencio, Bianca,Verli, Hugo,Vaz, Boniek G.,Li?o, Luciano M.,da Cunha, Luiz C.,Menegatti, Ricardo,Costa, Elson A.
, p. 1189 - 1206 (2018/07/31)
Nonsteroidal anti-inflammatory drugs are commonly used worldwide; however, they have several adverse effects, evidencing the need for the development of new, more effective and safe anti-inflammatory and analgesic drugs. This research aimed to design, syn
Synthesis and leishmanicidal activities of 1-(4-X-phenyl)-N′-[(4-Y- phenyl)methylene]-1H-pyrazole-4-carbohydrazides
Bernardino, Alice M.R.,Gomes, Adriana O.,Charret, Karen S.,Freitas, Antonio C.C.,Machado, Gerzia M.C.,Canto-Cavalheiro, Marilene M.,Leon, Leonor L.,Amaral, Veronica F.
, p. 80 - 87 (2007/10/03)
1H-pyrazole-4-carbohydrazides were synthesized and their leishmanicidal in vitro activities and cytotoxic effects were investigated. The drugs prototypes of these new compounds (ketoconazole, benznidazole, allopurinol and pentamidine) were also tested. It
