68299-60-5Relevant academic research and scientific papers
Synthesis of polycyclic xanthenes and furans via palladium-catalyzed cyclization of polycyclic aryltriflate esters
Wang, Ji-Quan,Harvey, Ronald G
, p. 5927 - 5931 (2002)
Palladium-catalyzed cyclization of polycyclic aromatic o-(arylmethyl)phenol triflate esters takes place with unexpected sulfur-oxygen bond cleavage to furnish polycyclic xanthenes. These are the first examples of Pd-catalyzed cross-coupling of aryl triflate esters with arenes to form diaryl ethers. In contrast, analogous palladium-catalyzed cyclization of polycyclic o-(aryloxy)phenol triflate esters proceeds via a mechanism that involves conventional carbon-oxygen bond cleavage to furnish diaryl furans.
4,4′-Unsymmetrically substituted 3,3′-biphenyl alpha helical proteomimetics as potential coactivator binding inhibitors
Weiser, Patrick T.,Chang, Ching-Yi,McDonnell, Donald P.,Hanson, Robert N.
, p. 917 - 926 (2014/01/23)
A series of unsymmetrically substituted biphenyl compounds was designed as alpha helical proteomimetics with the aim of inhibiting the binding of coactivator proteins to the nuclear hormone receptor coactivator binding domain. These compounds were synthes
