68313-46-2

Usage

Uses

Used in Pharmaceutical Industry:
4-Aminoquinoline-3-carboxylic acid is used as a building block for the synthesis of various pharmaceuticals due to its unique chemical structure and reactivity, contributing to the development of new drugs with potential therapeutic benefits.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Aminoquinoline-3-carboxylic acid serves as a key component in the creation of agrochemicals, leveraging its chemical properties to enhance crop protection and management.
Used in Antimalarial Applications:
4-Aminoquinoline-3-carboxylic acid is utilized as an antimalarial agent, given its demonstrated efficacy against the Plasmodium parasite responsible for malaria. Its antimalarial properties make it a significant compound in the search for new treatments and prophylactic measures against this global health issue.
Used in Antitumor Applications:
4-AMINOQUINOLINE-3-CARBOXYLIC ACID also shows promise in antitumor applications, as it has been studied for its potential to combat cancer. Its antitumor properties are currently under investigation, which could lead to its use in developing novel cancer therapies.
Overall, 4-Aminoquinoline-3-carboxylic acid is a versatile compound with a broad spectrum of applications across different fields, particularly医药 in the development of life-saving pharmaceuticals and improving agricultural practices.

InChI:InChI=1/C10H8N2O2/c11-9-6-3-1-2-4-8(6)12-5-7(9)10(13)14/h1-5H,(H2,11,12)(H,13,14)

Upstream product

• 75353-48-9 acide carbamoyl-4 quinoleinecarboxylique-3 
• 93074-72-7 ethyl 4-aminoquinoline-3-carboxylate 

Downstream Products

• 75353-53-6 amino-4 quinoleinecarboxylate de methyle-3 

Relevant academic research and scientific papers

Synthesis and in vitro biological evaluation of new polyamine conjugates as potential anticancer drugs

The synthesis of new polyamine derivatives containing dimeric quinoline (3a-c), cinnoline (4a-c) and phthalimide (7a-c and 8a-c) moieties is described. Three different polyamines: (1,4-bis(3-aminopropyl)piperazine (a), 4,9-dioxa-1,12-dodecanediamine (b), 3,3′-diamino-N-methyldipropylamine (c) were used as linkers. The new compounds were obtained according to known procedures. Their biological activity was assessed in vitro in a highly aggressive melanoma cell line A375. Polyamine diimides containing phthalimide moieties demonstrated no inhibitory activities against melanoma cells. Quinoline diamides were more efficient than cinnoline ones. Mainly cytostatic activity exerted as altered cell cycle profiles was observed at the concentrations causing about 50% reduction of adherent cell proliferation. Based on their structure as well as their biological activity, we assume that some of the newly synthesized compounds may act as DNA bisintercalators. This study might be useful for further designing and developing anticancer drugs with potent activities.

HETEROCYCLIC DERIVATIVES FOR TREATMENT OF HYPERLIPIDEMIA AND RELATED DISEASES

The present invention provides compositions adapted to enhance reverse cholesterol transport in mammals. The compositions are suitable for oral delivery and useful in the treatment and/or prevention of hypercholesterolemia, atherosclerosis and associated

Sur les orthoamino formyl quinoleines, nouveaux synthons heterocycliques

Les quatre orthoamino formyl quinoleines substituees sur le cycle pyridinique ont ete synthetisees par oxydation des amino hydroxymethyl quinoleines correspondantes.Parmi toutes les methodes envisagees, seule cette derniere a permis la preparation de l'amino-3 formyl-2 quinoleine, compose relativement peu stable.Ces nouveaux composes bifonctionnels derives de la qunoleine constituent des synthons particulierement interessants pour l'elaboration de certains heterocycles.