68313-59-7Relevant academic research and scientific papers
ACETALS OF LACTAMS AND ACID AMIDES. 41. ENAMINO AMIDES IN THE SYNTHESIS OF PYRIMIDINE DERIVATIVES
Ershov, L. V.,Kiselev, S. S.,Granik, V. G.
, p. 439 - 443 (2007/10/02)
The reaction of α-cyano-β-dimethylaminomethyleneacrylamide with arylamines was used to synthesize α-cyano-β-arylaminoacrylamides, which react readily with dimethylformamide diethylacetal to give the corresponding N-dimethylaminomethylene derivatives.The latter undergo cyclization to 1-aryl-5-cyano-4-pyrimidinones when they are heated in dimethylformamide or acetic anhydride and to pyrimidoquinolone derivatives when they are heated in glacial acetic acid.
