683209-03-2

Upstream product

• 17201-43-3 4-cyanobenzyl bromide 
• 683209-01-0 [4-((R)-1-Azido-but-3-enyl)-benzyl]-phosphonic acid diethyl ester 
• 683209-00-9 [4-((S)-1-Hydroxy-but-3-enyl)-benzyl]-phosphonic acid diethyl ester 
• 683209-02-1 [4-((R)-1-Amino-but-3-enyl)-benzyl]-phosphonic acid diethyl ester 
• 125185-25-3 (4-formylphenyl)methylphosphonic acid diethyl ester 
• 51359-78-5 4-(bromomethyl)benzaldehyde 
• 401810-35-3 (2S)-N-[(2S)-2-(naphthylmethyl)pent-4-enyl]-2-[(aminocyclohexyl)carbonylamino]-3-carbamoylpropanamide 
• 683208-97-1 [4-((R)-1-Phenoxycarbonylamino-but-3-enyl)-benzyl]-phosphonic acid diethyl ester 

Downstream Products

• 683209-05-4 [4-((Z)-(10R,15S,19S)-19-Carbamoylmethyl-15-naphthalen-1-ylmethyl-8,18,21-trioxo-7,9,17,20-tetraaza-spiro[5.15]henicos-12-en-10-yl)-benzyl]-phosphonic acid diethyl ester 
• 683209-04-3 [4-((E)-(10R,15S,19S)-19-Carbamoylmethyl-15-naphthalen-1-ylmethyl-8,18,21-trioxo-7,9,17,20-tetraaza-spiro[5.15]henicos-12-en-10-yl)-benzyl]-phosphonic acid diethyl ester 

Relevant academic research and scientific papers

Enantioselective Synthesis of Metathesis-Derived Ureapeptoid Macrocycles

Ring-closing metathesis (RCM) was used for the preparation of the first member of a new class of ureapeptoid-containing macrocycles. Key to the approach was the enantioselective synthesis of functionalized carbamoyl alkenylglycine equivalents using (-)-B-allyldiisopinocampheylborane [(-)-d-Ipc2Ball]-mediated asymmetric allylation.