125185-25-3

Usage

Uses

Used in Pharmaceutical Synthesis:
4-(Diethylphosphonomethyl)benzaldehyde is utilized as a key intermediate in the synthesis of pharmaceuticals. Its presence in the molecular structure of certain drugs aids in enhancing their therapeutic effects and pharmacological properties.
Used in Agrochemical Production:
In the agrochemical industry, 4-(Diethylphosphonomethyl)benzaldehyde is employed as a building block for the development of various agrochemicals. Its incorporation into these compounds contributes to their effectiveness in agricultural applications, such as pest control and crop protection.
Used in Material Sciences:
4-(Diethylphosphonomethyl)benzaldehyde also finds application in material sciences, where it serves as a component in the creation of novel materials with specific properties. Its unique structure allows it to be integrated into the design of materials with tailored characteristics for various uses.
Used in Organic Compound Production:
As a versatile building block, 4-(Diethylphosphonomethyl)benzaldehyde is used in the production of a wide range of organic compounds. Its ability to be modified and combined with other chemical entities makes it a valuable asset in organic chemistry for creating new and useful molecules.
Used in Medical Research and Drug Development:
4-(Diethylphosphonomethyl)benzaldehyde has been studied for its potential applications in medical research and drug development. Its unique structure and properties make it a promising candidate for the discovery and design of new therapeutic agents and diagnostic tools in the medical field.

Upstream product

• 60-29-7 diethyl ether 
• 125185-26-4 diethyl (4-(hydroxymethyl)benzyl)phosphonate 
• 28149-48-6 4-[(diethoxyphosphinyl)methyl]benzoic acid 
• 6232-88-8 4-bromomethylbenzoic Acid 
• 104-81-4 4-Methylbenzyl bromide 
• 3762-25-2 diethyl 4-methylbenzylphosphonate 
• 623-25-6 p-Xylylene dichloride 
• 25596-72-9 diethyl <4-(chloromethyl)benzyl> phosphonate 
• 108228-81-5 4-(diethoxyphosphorylmethyl)-1-bromomethyl-phenyl 
• 51359-78-5 4-(bromomethyl)benzaldehyde 
• 122-52-1 triethyl phosphite 
• 17201-43-3 4-cyanobenzyl bromide 

Downstream Products

• 683209-00-9 [4-((S)-1-Hydroxy-but-3-enyl)-benzyl]-phosphonic acid diethyl ester 
• 340741-62-0 (4-diethoxymethyl-benzyl)-phosphonic acid diethyl ester 
• 683209-03-2 {4-[(R)-1-(3-{1-[(S)-2-Carbamoyl-1-((S)-2-naphthalen-1-ylmethyl-pent-4-enylcarbamoyl)-ethylcarbamoyl]-cyclohexyl}-ureido)-but-3-enyl]-benzyl}-phosphonic acid diethyl ester 
• 683209-04-3 [4-((E)-(10R,15S,19S)-19-Carbamoylmethyl-15-naphthalen-1-ylmethyl-8,18,21-trioxo-7,9,17,20-tetraaza-spiro[5.15]henicos-12-en-10-yl)-benzyl]-phosphonic acid diethyl ester 
• 683209-05-4 [4-((Z)-(10R,15S,19S)-19-Carbamoylmethyl-15-naphthalen-1-ylmethyl-8,18,21-trioxo-7,9,17,20-tetraaza-spiro[5.15]henicos-12-en-10-yl)-benzyl]-phosphonic acid diethyl ester 
• 683208-97-1 [4-((R)-1-Phenoxycarbonylamino-but-3-enyl)-benzyl]-phosphonic acid diethyl ester 
• 651301-26-7 5-[4-(diethoxyphosphorylmethyl)phenyl]dipyrromethane 

Relevant academic research and scientific papers

Oligo(phenylene vinylene)-poly(methylstyrene) hybrids: Controlled step-wise molecular wiring of oligo(phenylene vinylene)

Well defined oligo(phenylene vinylene) grafted polymers known as oligo(phenylene vinylene)-poly(methylstyrene) hybrids have been developed using a step-wise synthetic protocol, where the length of the OPV can be controlled systematically to achieve specif

Synthesis, UV/vis spectra and electrochemical characterisation of arylthio and styryl substituted ferrocenes

Two series of substituted ferrocenes were synthesised using either the Horner-Wadswor th-Emmons reaction or monolithiation of ferrocene. The series consist of arylthio- and styryl-ferrocenes with different substituents in the para position of the aryl rings of the systems. The electronic communication was investigated by comparing the substituent effects in absorption spectroscopy and in cyclic voltammetry. A small substituent effect was found in the electronic transitions of the styryl substituted ferrocenes. The oxidation of the ferrocene derivatives showed clear substituent effects as illustrated by the linear Hammett plots. The effect was shown to be an order of magnitude larger in the arylthio-systems than in the styryl systems. It is suggested that the reason behind the large effect is a direct sulfur-iron orbital overlap. Versita Sp. z o.o.

Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces

A method of making a phosphono-substituted dipyrromethane comprises reacting an aldehyde or acetal having at least one phosphono group substituted thereon with pyrrole to produce a phosphono-substituted dipyrromethane; and wherein the phosphono is selecte

Synthesis of monophosphonic acid ligands with a phenanthroline core

The efficient synthesis of two diimine ligands incorporating one benzyl phosphonate group and a phenanthroline core is described. These functionalized ligands constitute a new type of linkers in hybrid organic-inorganic materials based on inorganic oxides and metallic complexes.

Porphyrins Bearing Mono or Tripodal Benzylphosphonic Acid Tethers for Attachment to Oxide Surfaces

The ability to attach redox-active molecules to oxide surfaces in controlled architectures (distance, orientation, packing density) is essential for the design of a variety of molecular-based information storage devices. We describe the synthesis of a series of redox-active molecules wherein each molecule bears a benzylphosphonic acid tether. The redox-active molecules include zinc porphyrins, a cobalt porphyrin, and a ferrocene-zinc porphyrin. An analogous tripodal tether has been prepared that is based on a tris [4-(dihydroxyphosphorylmethyl)phenyl]-derivatized methane. A zinc porphyrin is linked to the methane vertex by a 1,4-phenylene unit. The tripodal systems are designed to improve monolayer stability and ensure vertical orientation of the redox-active porphyrin on the electroactive surface. For comparison purposes, a zinc porphyrin bearing a hexylphosphonic acid tether also has been prepared. The synthetic approaches for introduction of the phosphonic acid group include derivatization of a bromoalkyl porphyrin or use of a dimethyl or diethyl phosphonate substituted precursor in a porphyrin-forming reaction. The latter approach makes use of dipyrromethane building blocks bearing mono or tripodal dialkyl phosphonate groups. The zinc porphyrintripodal compound bearing benzylphosphonic acid legs tethered to a SiO2 surface (grown on doped Si) was electrically well-behaved and exhibited characteristic porphyrin oxidation/reduction waves. Collectively, a variety of porphyrinic molecules can now be prepared with tethers of different length, composition, and structure (mono or tripodal) for studies of molecular-based information storage on oxide surfaces.

Enantioselective Synthesis of Metathesis-Derived Ureapeptoid Macrocycles

Ring-closing metathesis (RCM) was used for the preparation of the first member of a new class of ureapeptoid-containing macrocycles. Key to the approach was the enantioselective synthesis of functionalized carbamoyl alkenylglycine equivalents using (-)-B-allyldiisopinocampheylborane [(-)-d-Ipc2Ball]-mediated asymmetric allylation.

Phenyl glycines for use in reducing neurotoxic injury

A class of phenyl glycine compounds is described for treatment to reduce neurotoxic injury associated with anoxia or ischemia which typically follows stroke, cardiac arrest or perinatal asphyxia. The treatment includes administration of a phenyl glycine c