683233-14-9

Basic information

• Product Name: (R)-2-AMINOMETHYL-1-N-BOC-PIPERIDINE
• Synonyms: (R)-2-AMINOMETHYL-1-N-BOC-PIPERIDINE;(R)-2-AMINOMETHYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;(R)-TERT-BUTYL-2-(AMINOMETHYL)PIPERIDINE-1-CARBOXYLATE;(R)-2-Aminomethyl-N-Boc-piperidine;REF DUPL: 2-(Aminomethyl)-1-N-Boc-piperidine;tert-Butyl (2R)-2-(aminomethyl)piperidine-1-carboxylate;(R)-1-Boc-2-(aMinoMethyl)piperidine;(2R)-2-(Aminomethyl)piperidine,N1-BOCprotected
• CAS NO: 683233-14-9
• Molecular Formula: C₁₁H₂₂N₂O₂
• Molecular Weight: 214.3
• Mol File: 683233-14-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 299.4°C at 760 mmHg
• Flash Point: 134.9°C
• Appearance: /
• Density: 1.023
• Vapor Pressure: 0.00119mmHg at 25°C
• Refractive Index: 1.481
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 10.32±0.29(Predicted)
• CAS DataBase Reference: (R)-2-AMINOMETHYL-1-N-BOC-PIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-AMINOMETHYL-1-N-BOC-PIPERIDINE(683233-14-9)
• EPA Substance Registry System: (R)-2-AMINOMETHYL-1-N-BOC-PIPERIDINE(683233-14-9)

Safety Data

• Hazardous Substances Data: 683233-14-9(Hazardous Substances Data)

Usage

General Description

(R)-2-Aminomethyl-1-N-BOC-piperidine is a chemical compound often used in the field of organic chemistry. It is a derivative of piperidine, which is a widely used building block in pharmaceutical and chemical industries. The BOC (tert-butoxycarbonyl) in its name indicates that it is a BOC-protected compound. BOC is a protection group used commonly in organic synthesis which guards a functional group from potentially undesirable chemical transformations. The "(R)" indicates that it is a chiral molecule, and "2-aminomethyl" refers to the functional groups attached to the piperidine ring. Detailed properties such as its molecular weight, solubility, stability, and potential reactions can be found in its Material Safety Data Sheet (MSDS).

InChI:InChI=1/C11H22N2O2/c1-11(2,3)15-10(14)13-7-5-4-6-9(13)8-12/h9H,4-8,12H2,1-3H3/t9-/m1/s1

Downstream Products

• 783325-29-1 tert-butyl (2R)-2-[(methylamino)methyl]piperidine-1-carboxylate 
• 1187929-90-3 (R)-hexahydro-1H-pyrido[1,2-a]pyrazin-4(6H)-one 
• 1353975-00-4 (R)-benzyl ((1-(2-chloroacetyl)piperidin-2-yl)methyl)carbamate 
• 184044-09-5 (R)-benzyl (piperidin-2-ylmethyl)carbamate 

Relevant articles and documents

POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY

The present invention is to provide a novel compound (I), having the anti-virus activity, particularly the HIV integrase inhibitory activity, and a drug containing the same, particularly an anti-HIV drug, as well as a process and an intermediate thereof. Compound (I) wherein Z1 is NR4; R1 is hydrogen or lower alkyl; X is a single bond, a hetero atom group selected from O, S, SO, SO2 and NH, or lower alkylene or lower alkenylene in which the hetero atom group may intervene; R2 is optionally substituted aryl; R3 is hydrogen, a halogen, hydroxy, optionally substituted lower alkyl etc; and R4 and Z2 part taken together forms a ring, to form a polycyclic compound, including e.g., a tricyclic or tetracyclic compound.