68326-55-6

Basic information

• Product Name: (1R,2S,2S,5R)-2-isopropyl-5-methylcyclohexyl-1-(2'-methylbenzoate)
• CAS NO: 68326-55-6
• Molecular Weight: 274.403
• Mol File: 68326-55-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (1R,2S,2S,5R)-2-isopropyl-5-methylcyclohexyl-1-(2'-methylbenzoate)(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S,2S,5R)-2-isopropyl-5-methylcyclohexyl-1-(2'-methylbenzoate)(68326-55-6)
• EPA Substance Registry System: (1R,2S,2S,5R)-2-isopropyl-5-methylcyclohexyl-1-(2'-methylbenzoate)(68326-55-6)

Safety Data

• Hazardous Substances Data: 68326-55-6(Hazardous Substances Data)

Upstream product

• 2216-51-5 (-)-menthol 
• 933-88-0 ortho-toluoyl chloride 
• 118-90-1 ortho-methylbenzoic acid 
• 95-49-8 2-methylchlorobenzene 

Downstream Products

• 68326-62-5 2-((R)-Toluene-4-sulfinyl)-1-o-tolyl-ethanone 

Relevant articles and documents

Dimethylmalonyltrialkylphosphoranes: New general reagents for esterification reactions allowing controlled inversion or retention of configuration on chiral alcohols

A new class of trialkylphosphorane has been prepared through reaction of a trialkylphosphine with 2-chlorodimethylmalonate in the presence of triethylamine. These new reagents promote the condensation reaction of carboxylic acids with alcohols to provide esters along with trialkylphosphine oxide and dimethylmalonate. The condensation reaction of chiral secondary alcohols can be controlled to give either high levels of inversion or retention through a subtle interplay involving basicity of the reaction media, solvent, and tuning the electronic and steric nature of the carboxylic acid and steric nature of the phosphorane employed. A coherent mechanism is postulated to explain these observations involving reaction via an initial acyloxyphosphonium ion.