68327-01-5Relevant academic research and scientific papers
Syntheses and X-Ray Crystal Structures of Tricyclic Ketones Containing Trans-Fused Azabicyclooctane Units
Mori, Miwako,Saitoh, Fumihiko,Uesaka, Noriaki,Okamura, Kimio,Date, Tadamasa
, p. 4993 - 4998 (1994)
Tricyclic ketones containing the trans-fused 3-azabicyclooctane framework were prepared from the reactions of dienes and Cp2ZrBu2, followed by treatment with carbon monoxide.The structures were confirmed by X-ray analysis.
Synthesis of a rigidified bicyclic AAZTA-like ligand and relaxometric characterization of its GdIII complex
Martinelli, Jonathan,Martorana, Enrico,Tei, Lorenzo
supporting information, (2020/11/04)
The synthesis of a novel constrained polydentate ligand CpAAZTA derived from the heptadentate polyaminocarboxylic ligand AAZTA (6-amino-6-methylperhydro-1,4-diazepine-N, N’,N’’,N’’-tetraacetic acid) in which the ethylene bridge of the 1,4-diazepine ring i
Substituted Imidazopyridines as HDM2 Inhibitors
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Paragraph 0816, (2014/07/08)
The present invention provides substituted imidazopyridines as described herein or a pharmaceutically acceptable salt or solvate thereof. The representative compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same.
