68351-71-3

Upstream product

• 868-85-9 Dimethyl phosphite 
• 108-67-8 1,3,5-trimethyl-benzene 
• 576-83-0 2,4,6-trimethylphenyl bromide 
• 121-45-9 phosphorous acid trimethyl ester 
• 68351-67-7 (2,4,6-trimethyl-phenyl)-phosphonous acid dimethyl ester 
• 139139-80-3 bis(2,4,6-trimethylphenyl)iodonium triflate 

Downstream Products

• 68351-72-4 mes-phosphonate 
• 68351-73-5 2,4,6-trimethylphenylphosphonic acid 

Relevant academic research and scientific papers

C-P bond formation of cyclophanyl-, and aryl halides: Via a UV-induced photo Arbuzov reaction: A versatile portal to phosphonate-grafted scaffolds

A new versatile method for the C-P bond formation of (hetero)aryl halides with trimethyl phosphite via a UV-induced photo-Arbuzov reaction, accessing diverse phosphonate-grafted arenes, heteroarenes and co-facially stacked cyclophanes under mild reaction

Photoinduced Transition-Metal-Free Cross-Coupling of Aryl Halides with H-Phosphonates

Photoinduced transition-metal- and photosensitizer-free cross-coupling of aryl halides (including Ar-Cl, Ar-Br, and Ar-I) with H-phosphonates (including dialkyl phosphonates and diarylphosphine oxides) is reported. Various functional groups were tolerated, including ester, methoxy, dimethoxy, alkyl, phenyl, trifluoromethyl, and heterocyclic compounds. This simple and green strategy provides a practical pathway to synthesize arylphosphine oxides.

Copper-catalyzed P-arylation via direct coupling of diaryliodonium salts with phosphorus nucleophiles at room temperature

A new method for copper-catalyzed P-C bond formation through reaction of phosphorus nucleophiles with diaryliodonium salts at room temperature is described. Most target products are obtained with this method in high yields within a short reaction time of 10 min. It can be easily adapted to large-scale preparations. When unsymmetrical iodonium salts are employed, nucleophilic substitution occurs preferentially on the sterically hindered aromatic ring or the more electron-deficient ring.

Aryl-2,3-oxaphosphabicyclo[2.2.2]octene derivatives - The precursors of oxoarylphosphine oxides (aryl metaphosphonates)

The Baeyer-Villiger oxidation of 7-phosphanorbornene 7-oxides with sterically demanding substituents on the phosphorus atom (4a-d) by m-chloroperbenzoic acid afforded the title products (5a-d) as a mixture of two regioisomers (A and B). Isomer A, the resu

Oxidative Phoshonylation of Aromatics with Ammonium Cerium(IV) Nitrate

Arylphosphonates 5 and 6 can be prepared in good yields in a one-step synthesis starting from arenes with tri- or diethylphosphites and cerium ammonium nitrate (CAN) as oxidant.The seletivity of the oxidative phosphonylation is relatively low; the reactive species is a phosphite radical cation.