6836-83-5Relevant academic research and scientific papers
Base initiated aromatization/CO bond formation: A new entry to O-pyrazole polyfluoroarylated ethers
Tang, Xiangyang,Chang, Jing,Liu, Cuibo,Zhang, Bin
, p. 6534 - 6537 (2015/01/08)
A base initiated intermolecular SNAr reaction of pyrazolones with polyfluoroarenes was developed. The process involved the isomerization aromatization of pyrazolone followed by the CO bond formation via the selective CF bond cleavage. With this strategy, a wide range of O-pyrazole polyfluoroarylated ethers bearing diverse functional groups were synthesized in mild to good yields. Additionally, our method was also applied to the isoxazol substrates.
Microwave-assisted synthesis of substituted pyrazolones under solvent-free conditions
Mojtahedi, Mohammad M.,Jalali, Mohammad R.,Saeed Abaee,Bolourtchian, Mohammad
, p. 225 - 228 (2007/10/03)
Condensation of hydrazine derivatives with various β-keto esters under solvent-free conditions using microwave irradiation leads to very rapid formation of pyrazolones with good to excellent yields.
