683746-20-5Relevant academic research and scientific papers
Novel non-peptidic neuropeptide Y Y2 receptor antagonists
Jablonowski, Jill A.,Chai, Wenying,Li, Xiaobing,Rudolph, Dale A.,Murray, William V.,Youngman, Mark A.,Dax, Scott L.,Nepomuceno, Diane,Bonaventure, Pascal,Lovenberg, Timothy W.,Carruthers, Nicholas I.
, p. 1239 - 1242 (2007/10/03)
Through SAR studies of a piperidinylindoline cinnamide HTS lead, the first potent, non-peptide, low molecular weight selective Neuropeptide Y Y 2 (NPY Y2) antagonists have been synthesized. The SAR studies around the piperidinyl, the indolinyl, and the cinnamyl moieties are discussed.
