683771-95-1Relevant articles and documents
Syntheses of pyridin-4-ylium chirons: Applications in a synthesis of (+)-coniine
Roa, Luis F.,Gnecco, Dino,Galindo, Alberto,Teran, Joel L.,Bernes, Sylvain
, p. 847 - 850 (2004)
The compounds (3R,5S)-(+)-5-methyl-3-phenyl-2,3,5,6,7,8-hexahydro- oxazolo[3,2-a]pyridin-4-ylium iodide 4 and (3R,5S)-(+)-5-n-propyl-3-phenyl-2,3, 5,6,7,8-hexahydro-oxazolo[3,2-a]pyridin-4-ylium iodide 5 were synthesized in two steps starting from the bicyclic thiolactam trans (3R,2aS)-(-)-5-thio-3- phenyl-2,3,6,7,8,2a-hexahydro-oxazolo[3,2-a]pyridine 1. In addition, starting from 5 an enantiospecific synthesis of (+)-coniine 7 was achieved.