683774-10-9

Basic information

• Product Name: Cyclopentanecarboxylic acid, 2-[[(1R)-1-phenylethyl]amino]-, methyl ester, (1S,2R)-
• CAS NO: 683774-10-9
• Molecular Formula: C15H21NO2
• Molecular Weight: 247.337
• Mol File: 683774-10-9.mol

Chemical Properties

• CAS DataBase Reference: Cyclopentanecarboxylic acid, 2-[[(1R)-1-phenylethyl]amino]-, methyl ester, (1S,2R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopentanecarboxylic acid, 2-[[(1R)-1-phenylethyl]amino]-, methyl ester, (1S,2R)-(683774-10-9)
• EPA Substance Registry System: Cyclopentanecarboxylic acid, 2-[[(1R)-1-phenylethyl]amino]-, methyl ester, (1S,2R)-(683774-10-9)

Safety Data

• Hazardous Substances Data: 683774-10-9(Hazardous Substances Data)

Upstream product

• 120-92-3 cyclopentanone 
• 683774-02-9 methyl 2-{[(R)-1-phenylethyl]amino}cyclopent-1-ene-1-carboxylate 

Relevant articles and documents

Synthesis, preliminary biological evaluation and molecular modeling of some new heterocyclic inhibitors of TACE

Central heteroaryl ring analogues belonging to a series of potent hydroxamate TACE inhibitors were synthesized. The TACE inhibitory activities of these compounds were evaluated by in vitro WBA and in silico molecular modeling studies using crystal structure of human TACE. Compound 14 showed very good in vitro inhibition, supported by the in silico docking studies.

Asymmetric catalytic hydrogenation process for preparation of chiral cyclic beta-aminoesters

A novel process for the asymmetric synthesis of substituted cyclic β-amino-carboxylates of the type shown in the specification from appropriate β-enamino-ester starting materials is described. These compounds are useful as intermediates for MMP and TACE i