68406-49-5Relevant academic research and scientific papers
DERIVATIVES OF QUINOLINES AND QUINOXALINES AS PROTEIN TYROSINE KINASE INHIBITORS
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Page/Page column 77, (2009/12/27)
The invention relates to compounds of Formula (I), wherein the substituens are as defined in the specification, in free form or in the form of a pharmaceutically acceptable salt, solvate, ester, N-oxide thereof; processes for the preparation thereof; to p
Nitroimidazoles: Part XVIII- Mannich Reactions of Azomycin-2-nitro-4,5-bisaminoalkylimidazoles
Parthasarathy, P. C.,Desai, H. K.,Saindane, M. T.
, p. 157 (2007/10/02)
Mannich reaction of azomycin (1) (2-nitroimidazole) gives 4-monoaminoalkyl (2) or 4,5-bisaminoalkyl derivatives (4a and 4c) in preference to N-substituted compounds.Methylation of 4a affords the 1-methyl derivative (4b).The structures of these products are based on spectroscopic evidences.
