68409-20-1

Basic information

• Product Name: 6-(2,5-Dimethoxy-4-methylbenzoyl)-2-methoxybenzoesaeure-methylester
• CAS NO: 68409-20-1
• Molecular Weight: 344.364
• Mol File: 68409-20-1.mol

Chemical Properties

• CAS DataBase Reference: 6-(2,5-Dimethoxy-4-methylbenzoyl)-2-methoxybenzoesaeure-methylester(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(2,5-Dimethoxy-4-methylbenzoyl)-2-methoxybenzoesaeure-methylester(68409-20-1)
• EPA Substance Registry System: 6-(2,5-Dimethoxy-4-methylbenzoyl)-2-methoxybenzoesaeure-methylester(68409-20-1)

Safety Data

• Hazardous Substances Data: 68409-20-1(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 14963-96-3 3-methoxyphthalic anhydride 
• 13321-74-9 1-bromo-2,5-dimethoxy-4-methylbenzene 
• 180578-98-7 2,5-dimethoxy-4-methylphenylmagnesium bromide 
• 68409-19-8 3-(2,5-Dimethoxy-4-methylphenyl)-3-hydroxy-7-methoxy-1(3H)-isobenzofuranon 

Relevant articles and documents

Regioselective Addition of Grignard Reagents to 3-Methoxy- and 3-Nitrophthalic Anhydride

The regioselectivity in the addition of the grignard reagents 5a and 6a to the anhydrides 1 and 2 is determined by the solvent system: in a highly selective manner (3:97), the meta carbonyl group is attacked in tetrahydrofuran/tetramethylethylenediamine, while predominant, but relatively unselective (maximum 78:22) addition to the ortho carbonyl group is observed in diethyl ether.The influence of the solvent system on the regioselectivity is discussed.The LUMO-coefficients of the carbonyl carbon atoms in 1 and 2 were calculated.