68415-29-2

Upstream product

• 68612-32-8 6-(4-fluoro-phenyl)-4-methyl-2H-pyridazin-3-one 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 19064-64-3 3,6-dichloro-4-methylpyridazine 
• 1765-93-1 4-fluoroboronic acid 

Downstream Products

• 76970-10-0 6-(4-Fluoro-phenyl)-3,8-dimethyl-[1,2,4]triazolo[4,3-b]pyridazine 
• 118269-88-8 [6-(4-Fluoro-phenyl)-4-methyl-pyridazin-3-yl]-(2-morpholin-4-yl-ethyl)-amine; hydrochloride 

Relevant academic research and scientific papers

SUBSTITUTED IMIDAZO[1,2-b]PYRIDAZINES, SUBSTITUTED IMIDAZO[1,5-b]PYRIDAZINES, RELATED COMPOUNDS, AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS

The invention provides substituted imidazo[1,2-b]pyridazine compounds, substituted imidazo[1,5-b]pyridazine compounds, related compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., Gaucher disease, Parkinson's disease, Lewy body disease, dementia, or multiple system atrophy, in a patient. Exemplary substituted imidazo[1,2-b]pyridazine compounds described herein include substituted imidazo[1,2-b]pyridazine-3-carboxamide compounds and variants thereof.

3-Aminopyridazine derivatives with atypical antidepressant, serotonergic, and dopaminergic activities

Minaprine [3[(β-morpholinoethyl)amino]4-methyl-6-phenylpyridazine dihydrochloride] is active in most animal models of depression and exhibits in vivo a dual dopaminomimetic and serotoninomimetic activity profile. In an attempt to dissociate these two effe