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6,7-Dihydro-5H-pyrrolo[3,4-d]pyrimidine-2,4-diol is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

684202-26-4

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684202-26-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 684202-26-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,8,4,2,0 and 2 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 684202-26:
(8*6)+(7*8)+(6*4)+(5*2)+(4*0)+(3*2)+(2*2)+(1*6)=154
154 % 10 = 4
So 684202-26-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H7N3O2.ClH/c10-5-3-1-7-2-4(3)8-6(11)9-5;/h7H,1-2H2,(H2,8,9,10,11);1H

684202-26-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 6,7-Dihydro-5H-pyrrolo[3,4-d]pyrimidine-2,4-diol

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:684202-26-4 SDS

684202-26-4Downstream Products

684202-26-4Relevant academic research and scientific papers

(S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: Further Exploration of Bioisosteric Replacements and Structural and Biological Investigation

Brogi, Simone,Brindisi, Margherita,Butini, Stefania,Kshirsagar, Giridhar U.,Maramai, Samuele,Chemi, Giulia,Gemma, Sandra,Campiani, Giuseppe,Novellino, Ettore,Fiorenzani, Paolo,Pinassi, Jessica,Aloisi, Anna Maria,Gynther, Mikko,Venskutonyte, Raminta,Han, Liwei,Frydenvang, Karla,Kastrup, Jette Sandholm,Pickering, Darryl S.

supporting information, p. 2124 - 2130 (2018/03/21)

Starting from 1-4 and 7 structural templates, analogues based on bioisosteric replacements (5a-c vs 1, 2 and 6 vs 7) were synthesized for completing the SAR analysis. Interesting binding properties at GluA2, GluK1, and GluK3 receptors were discovered. The requirements for GluK3 interaction were elucidated by determining the X-ray structures of the GluK3-LBD with 2 and 5c and by computational studies. Antinociceptive potential was demonstrated for GluK1 partial agonist 3 and antagonist 7 (2 mg/kg ip).

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