68422-00-4

Usage

Uses

Used in Pharmaceutical Applications:
Sarsasapogenin 3-O-β-D-galactopyranosid is used as a pharmaceutical agent for its potential anticancer properties. It has been shown to exhibit bioactivities against certain human tumor processes, making it a candidate for the development of novel anticancer drugs. Its ability to modulate cellular signaling pathways and induce apoptosis in cancer cells contributes to its potential therapeutic value.
Used in Drug Delivery Systems:
In the field of drug delivery, Sarsasapogenin 3-O-β-D-galactopyranosid is utilized as a carrier molecule to improve the solubility, bioavailability, and targeted delivery of various therapeutic agents. Its natural foaming properties and glycosylation can enhance the stability and efficacy of drug formulations, particularly for those that require improved water solubility or targeted release.
Used in Traditional Medicine:
Sarsasapogenin 3-O-β-D-galactopyranosid has a long history of use in traditional medicine, where it is valued for its potential to support overall health and well-being. Its inclusion in herbal remedies and tonics is attributed to its purported benefits in promoting vitality and strength, as well as its potential to support the immune system and overall health.
Used in Cosmetics and Personal Care:
In the cosmetics and personal care industry, Sarsasapogenin 3-O-β-D-galactopyranosid is used as an active ingredient for its potential skin conditioning and moisturizing properties. Its ability to enhance skin hydration and improve skin barrier function makes it a valuable addition to skincare products, particularly those aimed at addressing dryness and promoting a healthy skin appearance.
Used in Functional Foods and Supplements:
Sarsasapogenin 3-O-β-D-galactopyranosid is also used in the development of functional foods and dietary supplements, where its potential health-promoting properties are leveraged to provide consumers with added health benefits. Its inclusion in these products is based on its potential to support immune function, promote overall health, and contribute to a balanced diet.

Upstream product

• 142759-74-8 anemarrhenasaponin IV 
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• 615570-19-9 3,6-di-O-benzoylated-isopropyl-β-D-1-thiogalactopyranoside 
• 367-93-1 isopropyl β-D-thiogalactopyranoside 
• 107800-07-7 C₅₃H₇₈O₂₀ 
• 41059-79-4 melongoside E 
• 28154-24-7 C₄₁H₆₂O₁₂ 

Relevant academic research and scientific papers

New transformation pathway and cytotoxic derivatives from the acid hydrolysis of timosaponin B III

Timosaponin B III is a major bioactive steroidal saponin isolated from Anemarrhena asphodeloides Bge. To potentially discover derivatives with better biological activity, timosaponin B III was structurally modified via acid hydrolysis to yield one new (2, timopregnane A I) C21 steroidal glycoside and seven known compounds. Their structures were elucidated on the basis of NMR spectroscopy and mass spectrometry. All eight compounds were evaluated for cytotoxic activity against MCF7, SW480, HepG2, and SGC7901 cell lines in vitro. As a result, compounds 6 and 7 showed significant activity (IC50 2.94–12.2 μM) against all tested cell lines. Structure–activity relationships of these compounds were investigated and the preliminary conclusions were provided. Moreover, a new transformation pathway was discovered in the acid hydrolysis of timosaponin B III for the first time.

TIMOSAPONIN COMPOUNDS

Provided herein are timosaponin compounds of Frmula I, II, IIΙ, I', II' and IIΙ', pharmaceutical compositions comprising the coumpounds, and processes of preparation thereof. Also provided are uses of said timosaponin compounds for preparing medicament for the treatment of diseases associated with beta-amyloid in hosts or subjects in need thereof.

MELONGOSIDE L AND MELONGOSIDE M, STEROIDAL SAPONINS FROM SOLANUM MELONGENA SEEDS

Two new steroidal saponins, melongoside L and melongoside M, have been isolated from a methanolic extract of Solanum melongena seeds and their structures elucidated.Key Word Index - Solanum melongena; Solanaceae; spirostanol glycosides; melongoside L; melongoside M.

STEROID GLYCOSIDES OF THE SEEDS OF Solanum melongena. STRUCTURES OF MELONGOSIDES A, B, E, F, AND H

Three chromatographically individual fractions, each containing tigogenin glycosides and diosgenin glycosides have been isolated by chromatography on a silica gel column from a methanolic extract of eggplant seeds.To separate the mixture of two difficultly separable glycosides into individual components, each fraction was acetylated and epoxidated, and the derivatives obtained were separated chromatographically.The tigogenin glycoside peracetates isolated were saponified, and the diosgenin epoxide glycoside acetates were de-epoxidated and saponified, to give the individual glycosides, melongosides A, B, E, F, and H.The complete chemical structure of each melongoside has been shown with the aid of acid hydrolysis, methylation, and periodate oxidation followed by a study of the products obtained.