684233-26-9Relevant academic research and scientific papers
Semisynthesis of an analogue of antitumor bicyclic hexapeptide RA-VII by fixing the Ala-2/Tyr-3 bond to cis by incorporating a triazole cis-amide bond surrogate
Hitotsuyanagi, Yukio,Motegi, Shuichi,Hasuda, Tomoyo,Takeya, Koichi
, p. 1111 - 1114 (2007/10/03)
We prepared an analogue of an antitumor bicyclic hexapeptide RA-VII whose amide configuration between residues 2 and 3 was fixed to cis by incorporating a triazole cis-amide bond surrogate. This analogue was shown, by NMR studies, to take almost the same
