684284-46-6Relevant academic research and scientific papers
Effect of substitution on novel tricyclic HIV-1 integrase inhibitors
Fardis, Maria,Jin, Haolun,Jabri, Salman,Cai, Ruby Z.,Mish, Michael,Tsiang, Manuel,Kim, Choung U.
, p. 4031 - 4035 (2007/10/03)
A series of novel tricyclic inhibitors of HIV-1 integrase enzyme was prepared. The effect of substitution at C-6 of the 9-hydroxy-6,7-dihydropyrrolo[3,4-g]quinolin-8-one compounds was studied in vitro. Inhibitors with small side chains at C-6 were general
PHOSPHONATE ANALOGS OF HIV INTEGRASE INHIBITOR COMPOUNDS
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Page/Page column 434-435, (2010/02/15)
Novel HIV integrase inhibitor compounds having at least one phosphonate group, protected intermediates thereof, and methods for inhibition of HIV-integrase are disclosed.
