684285-11-8Relevant academic research and scientific papers
Design, synthesis, and SAR studies of novel and highly active tri-cyclic HIV integrase inhibitors
Jin, Haolun,Cai, Ruby Z.,Schacherer, Laura,Jabri, Salman,Tsiang, Manuel,Fardis, Maria,Chen, Xiaowu,Chen, James M.,Kim, Choung U.
, p. 3989 - 3992 (2007/10/03)
A novel class of tri-cyclic HIV integrase inhibitors were designed based on conformational analysis of 1,6-naphthyridine carboxamide compound L-870810 and docking the designed inhibitor into the active site of our integrase enzyme model. The efficient syn
PHOSPHONATE ANALOGS OF HIV INTEGRASE INHIBITOR COMPOUNDS
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Page/Page column 434-435, (2010/02/15)
Novel HIV integrase inhibitor compounds having at least one phosphonate group, protected intermediates thereof, and methods for inhibition of HIV-integrase are disclosed.
