68454-22-8

Upstream product

• 108-46-3 recorcinol 
• 70-11-1 α-bromoacetophenone 
• 90-33-5 7-hydroxy-4-methyl-chromen-2-one 
• 13196-08-2 3-phenyl-benzofuran-6-ol 
• 141-97-9 ethyl acetoacetate 
• 68454-21-7 4-methyl-7-(2-oxo-2-phenylethoxy)-2H-1-benzopyran-2-one 
• 64-17-5 ethanol 
• 141-52-6 sodium ethanolate 

Downstream Products

• 478413-83-1 2-bromo-5-methyl-3-phenyl-furo[3,2-g]chromen-7-one 

Relevant academic research and scientific papers

Psoralen benzenesulfonate derivatives and application thereof

The invention relates to a preparation method and application of psoralen benzenesulfonate derivatives, and the compounds are (7-oxo-3-phenyl-7H-furan [3, 2-g] benzofuran-5-) methanesulfonate (compound 7) and compound 7a-7ad. The influence of the 31 psoralen benzenesulfonate derivatives on the generation of melanin in mouse B16 cells is also investigated. Results show that the compounds 7e, 7i, 7m-7n, 7t-7u, 7w and 7y can be clinically used for preparing medicines for treating leucoderma.

Preparation of novel 1,2,3-triazole furocoumarin derivatives via click chemistry and their anti-vitiligo activity

The extracts of Psoralea corylifolia?L. were often used for the repigmentation of leukoderma (vitiligo) in traditional Uygur medicine thousands years ago. Nowadays, its active ingredient, furocoumarins, has been clinically applied since it exhibited stron

Psoralen derivative containing phenyl triazole and application

The invention relates to a psoralen derivative containing phenyl triazole and application. The derivative is 4-methyl-7-hydroxyl coumarin (midbody 1); 4-methyl-7-(2-oxo) phenyl ethyoxyl coumarin (midbody 2); 5-methyl-3-phenyl psoralen (midbody 3); 7-oxo-3

Studies in synthesis of new psoralenamines

(Chemical Equation Presented) New amino psoralen derivatives have been synthesized via bromination. Bromination of 3,5-substituted psoralens has been studied. The second position of the furan ring is more susceptible to bromination than the α-position of

An efficient and convenient synthesis of furocoumarins via Pechmann reaction on ZnCl2/Al2O3 under microwave irradiation

Furocoumarins were rapidly synthesized via Pechmann condensation of 6-hydroxybenzofurans with ethylacetoacetate catalyzed by ZnCl2/Al2O3 under solvent-free condition.