60504-85-0Relevant academic research and scientific papers
Improved synthesis of dicyclohexylidene protected quebrachitol and its use in the synthesis of l-chiro-inositol derivatives
Baars, Sylvia M.,Hoberg, John O.
, p. 1680 - 1684 (2007/10/03)
A modified synthesis of 1l-1,2:3,4-di-O-cyclohexylidene-5-O-methyl-chiro-inositol has been accomplished that improves the overall procedure, yield, and environmental aspects of its formation. Several inositol analogues have been prepared from this intermediate for testing as biosynthetic inhibitors of glycosyl-phosphatidylinositol (GPI) anchor formation.
A Chiral Synthesis of D-myo-Inositol 1-Phosphate Starting from L-Quebrachitol
Akiyama, Takahiko,Takechi, Naoto,Ozaki, Shoichiro,Shiota, Kenji
, p. 366 - 372 (2007/10/02)
A naturally occurring optically active cyclitol, L-quebrachitol (1L-2-O-methyl-chiro-inositol), was stereoselectively transformed into myo-inositol derivatives via an oxidation-reduction process.The methyl ether was cleaved chemoselectively with AlCl3NaI
Chiral synthesis of D-Myo-inositol 1-phosphate starting from L-querbrachitol
Akiyama,Takechi,Ozaki
, p. 1433 - 1434 (2007/10/02)
D-Myo-inositol 1-phosphate was synthesized from L-quebrachitol via stereoselective inversion of a 3-hydroxyl group and chemoselective demethylation.
