68480-30-8

Usage

InChI:InChI=1/C11H19NOS.ClH/c1-2-3-4-5-6-7-9-12-11(13)8-10-14-12;/h8,10H,2-7,9H2,1H3;1H

Upstream product

• 19014-38-1 N,N'-Di(n-octyl)-3,3'-thiodipropionamid 
• 33312-01-5 3,3'-disulfanediylbis(N-octylpropanamide) 
• 7791-25-5 sulfuryl dichloride 

Relevant academic research and scientific papers

A SUCCESSIVE PREPARATION METHOD OF 3-ISOTHIAZOLONE DERIVATES AND THEIR INTERMEDIATES

The present application provides a process for continuously producing 3-isothiazolinone derivatives and intermediate products thereof, comprising continuously carrying out four steps, i.e., sulfuration, purification, amination and chlorination. Compared with the batch process of the prior art, the process of the present application may reduce the amount of manufacturing devices, lower energy consumption, simplify operations, and is therefore particularly suitable for mass production.

Process for preparing 4-isothiazolin-3-one

The present invention relates to an improved process for selectively preparing 4-isothiazolin-3-one having the following structural formula(I), consisted of preparing 3,3'-dithiodipropionyldichloride by reacting 3,3'-dithiodipropionic acid with thionylchloride, reacting with amine compound to prepare 3,3'-dithiodipropioneamide, and herein adding sulfrylchloride in organic solvent to cyclize, which is useful as antiseptic or anti-infectives for cooling water, metal processing oils, paints, cosmetics, surfactants, sensitizers, etc. STR1 wherein, R1 is methyl or n-octyl group; R2 is hydrogen or chlorine atom.