33312-01-5

Basic information

• Product Name: 3,3'-Dithiobis(N-octylpropionamide)
• Synonyms: 3,3'-dithiobis[N-octylpropionamide];N,N'-Bis-n-octyl-3,3'-dithiopropionamide;N-Octyl-3-[3-(octylamino)-3-oxopropyl]disulfanylpropanamide;3,3'-Disulfanediylbis(N-octylpropanamide);3,3'-Dithiobis[N-octylpropanaMide
• CAS NO: 33312-01-5
• Molecular Formula: C₂₂H₄₄N₂O₂S₂
• Molecular Weight: 432.73
• EINECS: 251-453-8
• Mol File: 33312-01-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 619.6 °C at 760 mmHg
• Flash Point: 328.5 °C
• Appearance: /
• Density: 1.003 g/cm³
• PKA: 15.57±0.46(Predicted)
• CAS DataBase Reference: 3,3'-Dithiobis(N-octylpropionamide)(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3'-Dithiobis(N-octylpropionamide)(33312-01-5)
• EPA Substance Registry System: 3,3'-Dithiobis(N-octylpropionamide)(33312-01-5)

Safety Data

• Hazardous Substances Data: 33312-01-5(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Uses

N,N’-Di-n-octyl-3,3’-dithiodipropionamide (cas# 33312-01-5) is a compound useful in organic synthesis.

Upstream product

• 111-86-4 n-Octylamine 
• 1002-18-2 3-(2-chlorocarbonyl-ethyldisulfanyl)-propionyl chloride 
• 1119-62-6 3,3'-dithiobis(propionic acid) 
• 15441-06-2 dimethyl 3,3'-dithiodipropionate 

Downstream Products

• 64359-81-5 Sea-Nine 211 
• 26530-20-1 2-octyl-isothiazol-3-one 
• 68480-30-8 2-n-octyl-4-isothiazolin-3-one.HCl 
• 26530-24-5 5-chloro-2-octyl-2H-isothiazol-3-one 

Relevant articles and documents

Preparation method of 4, 5-dichloro-2-n-octyl-3-isothiazolinone

The invention discloses a preparation method of 4, 5-dichloro-2-n-octyl-3-isothiazolinone. The preparation method comprises the following steps: 1) carrying out a reaction on dimethyl dithiodipropionate and n-octylamine to obtain 3, 3'-dithiodioctyl propionamide; and 2) carrying out a reaction on the 3, 3'-dithio dioctyl propionamide and phosphorus oxychloride, so as to obtain the 4, 5-dichloro-2-n-octyl-3-isothiazolinone. The preparation method of the 4, 5-dichloro-2-n-octyl-3-isothiazolinone provided by the invention is simple, impurities are not introduced in the process, the product purity is high, the production is environment-friendly and safe, and the market application prospect is wide.

Preparation of N-Substituted Isothiazolinone Derivatives

Provided is a process for the preparation of an N-substituted isothiazolinone derivative having the general formula (I), comprising reacting N-substituted 3-mercaptopropionamides of formula (II) or N,N′-bis-substituted 3,3′-dithiodipropionamides of formula (III) with sulfuryl chloride in the absence of solvents. Also provided is a process for the preparation of a compound having the general formula (III), comprising reacting a methyl ester of formula (IV) with an amine of formula (V) in a solvent of methanol. As no addition solvent is used in the process of the invention, the cost of manufacturing and pollution to the environment can be reduced.