33312-01-5

Usage

Uses

Used in Organic Synthesis:
3,3'-Dithiobis(N-octylpropionamide) is used as a reagent in organic synthesis for various chemical reactions. Its unique structure allows it to act as a versatile building block, facilitating the formation of new compounds and improving the efficiency of certain reactions.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3,3'-Dithiobis(N-octylpropionamide) is used as an intermediate in the synthesis of various drugs and drug candidates. Its ability to form stable bonds with other molecules makes it a valuable component in the development of new therapeutic agents.
Used in Chemical Research:
3,3'-Dithiobis(N-octylpropionamide) is also utilized in chemical research as a model compound to study the properties and behavior of similar organic compounds. This helps researchers gain insights into the structure-activity relationships and potential applications of related compounds.
Used in Material Science:
In the field of material science, 3,3'-Dithiobis(N-octylpropionamide) is employed in the development of new materials with specific properties. Its unique structure and reactivity can contribute to the creation of advanced materials with applications in various industries, such as electronics, coatings, and adhesives.

Upstream product

• 111-86-4 n-Octylamine 
• 15441-06-2 dimethyl 3,3'-dithiodipropionate 
• 1119-62-6 3,3'-dithiobis(propionic acid) 
• 1002-18-2 3-(2-chlorocarbonyl-ethyldisulfanyl)-propionyl chloride 

Downstream Products

• 68480-30-8 2-n-octyl-4-isothiazolin-3-one.HCl 
• 64359-81-5 Sea-Nine 211 
• 26530-20-1 2-octyl-isothiazol-3-one 
• 26530-24-5 5-chloro-2-octyl-2H-isothiazol-3-one 

Relevant academic research and scientific papers

Conformation, and Charge Tunneling through Molecules in SAMs

This paper demonstrates that the molecular conformation (in addition to the composition and structure) of molecules making up self-assembled monolayers (SAMs) influences the rates of charge tunneling (CT) through them, in molecular junctions of the form AuTS/S(CH2)2CONR1R2//Ga2O3/EGaIn, where R1 and R2 are alkyl chains of different length. The lengths of chains R1 and R2 were selected to influence the conformations and conformational homogeneity of the molecules in the monolayer. The conformations of the molecules influence the thickness of the monolayer (i.e. tunneling barrier width) and their rectification ratios at ±1.0 V. When R1 = H, the molecules are well ordered and exist predominantly in trans-extended conformations. When R1 is an alkyl group (e.g., R1 H), however, their conformations can no longer be all-trans-extended, and the molecules adopt more gauche dihedral angles. This change in the type of conformation decreases the conformational order and influences the rates of tunneling. When R1 = R2, the rates of CT decrease (up to 6.3×), relative to rates of CT observed through SAMs having the same total chain lengths, or thicknesses, when R1 = H. When R1 H R2, there is a weaker correlation (relative to that when R1 = H or R1 = R2) between current density and chain length or monolayer thickness, and in some cases the rates of CT through SAMs made from molecules with different R2 groups are different, even when the thicknesses of the SAMs (as determined by XPS) are the same. These results indicate that the thickness of a monolayer composed of insulating, amide-containing alkanethiols does not solely determine the rate of CT, and rates of charge tunneling are influenced by the conformation of the molecules making up the junction.

Preparation method of 4, 5-dichloro-2-n-octyl-3-isothiazolinone

The invention discloses a preparation method of 4, 5-dichloro-2-n-octyl-3-isothiazolinone. The preparation method comprises the following steps: 1) carrying out a reaction on dimethyl dithiodipropionate and n-octylamine to obtain 3, 3'-dithiodioctyl propionamide; and 2) carrying out a reaction on the 3, 3'-dithio dioctyl propionamide and phosphorus oxychloride, so as to obtain the 4, 5-dichloro-2-n-octyl-3-isothiazolinone. The preparation method of the 4, 5-dichloro-2-n-octyl-3-isothiazolinone provided by the invention is simple, impurities are not introduced in the process, the product purity is high, the production is environment-friendly and safe, and the market application prospect is wide.

Preparation of N-Substituted Isothiazolinone Derivatives

Provided is a process for the preparation of an N-substituted isothiazolinone derivative having the general formula (I), comprising reacting N-substituted 3-mercaptopropionamides of formula (II) or N,N′-bis-substituted 3,3′-dithiodipropionamides of formula (III) with sulfuryl chloride in the absence of solvents. Also provided is a process for the preparation of a compound having the general formula (III), comprising reacting a methyl ester of formula (IV) with an amine of formula (V) in a solvent of methanol. As no addition solvent is used in the process of the invention, the cost of manufacturing and pollution to the environment can be reduced.