68484-90-2

Upstream product

• 103-82-2 phenylacetic acid 
• 3082-75-5 L-Alanine ethyl ester 
• 17344-99-9 AlaOEt 
• 103-80-0 phenylacetyl chloride 

Downstream Products

• 1345962-81-3 2-benzyl-5-hydroxy-6-methylpyridine-3,4-dicarboxylic acid dimethyl ester 
• 1345962-46-0 2-benzyl-5-hydroxy-6-methylpyridine-3,4-dicarboxylic acid 
• 1345962-90-4 ethyl 4-acetyl-2-benzyl-5-hydroxy-6-methylnicotinate 
• 1345962-55-1 4-acetyl-2-benzyl-5-hydroxy-6-methylnicotinic acid 
• 68484-91-3 2-benzyl-4-methyl-5-ethoxy-1,3-oxazole 

Relevant academic research and scientific papers

Design and synthesis of potent and selective P2X3 receptor antagonists derived from PPADS as potential pain modulators

Pyridoxalphosphate-6-azophenyl-2′,4′-disulfonate (7a, PPADS), a nonselective P2X receptor antagonist, was extensively modified to develop more stable, potent, and selective P2X3 receptor antagonists as potential antinociceptive agents. Based on

NOVEL PYRIDINE CARBOXYLIC ACID BASED COMPOUND USED AS A P2X1 AND P2X3 RECEPTOR ANTAGONIST, A PRODUCTION METHOD FOR THE SAME AND A COMPOSITION COMPRISING THE SAME

Provided are a novel pyridine carboxylic acid based compound used as a P2X1 and P2X3 receptor antagonist, a production method for the same and a composition comprising the same. The compound according to the present invention is a powerful antagonist of P2X1 and P2X3 receptors, and hence can be used as a drug for treating or preventing diseases involving neurological pain or chronic inflammatory diseases which are diseases caused by P2X1 and P2X3 receptor activity.