68490-12-0

Upstream product

• 109-65-9 1-bromo-butane 
• 139-85-5 3,4-dihydroxybenzaldehyde 
• 542-69-8 1-iodo-butane 
• 121-33-5 vanillin 

Downstream Products

• 85259-15-0 (3,4-Dibutoxy-phenyl)-hydroxy-acetic acid 
• 206536-14-3 3,4-dibutoxy-benzoic acid 
• 85259-02-5 5-(3,4-Dibutoxy-phenyl)-2-imino-thiazolidin-4-one 
• 79712-13-3 5-(3,4-Dibutoxy-phenyl)-thiazolidine-2,4-dione 
• 1620237-92-4 C₁₉H₂₃Cl₂NO₄S 
• 1620237-91-3 C₂₅H₂₉NO₅ 
• 1620237-90-2 C₂₂H₂₈O₄ 
• 68490-11-9 C₁₅H₂₄O₃ 
• 1585970-41-7 C₂₃H₂₇NO₂ 

Relevant academic research and scientific papers

Nano-Assemblies from J-Aggregated Dyes: A Stimuli-Responsive Tool Applicable to Living Systems

Controlling the packing arrangements of dyes is a facile way of tuning their photophysical and/or photochemical properties, thus enabling new sensing mechanisms for photofunctional tools. Here, we present a general and robust strategy toward water-stable

Synthesis and mesomorphic characterization of some novel steroidal mesogens: A structure–property correlation

The steroidal derivatives are found to be extremely good mesogens since their inception. Because of their inherent chirality, they have the potential to induce a wide variety of liquid crystalline phases, including frustrated phases depending upon the structure of the steroidal skeleton and the substituents attached. In this report, a series of novel monoalkoxy and dialkoxy benzoate derivatives of ergosterol and a few monoalkoxy derivatives of stigmasterol have been synthesized and their mesomorphic property has been investigated. The derivatives exhibited various mesophases including SmA, SmC*, N*, TGB and blue phases. Also, the gelation ability of some of these derivatives with various organic solvents has been examined. Furthermore, the mesomorphism of these derivatives has been compared with the analogous cholesteryl counterparts.

Influence of different linkages on the mesomorphic properties of aromatic ring system liquid crystals

In order to study the effect of the central linkage on the mesomorphic behaviour of aromatic ring liquid crystals we have synthesized two homologues groups, group A includes compounds 1a-d and group B includes compounds 2a-e. Group A has azo, azomethine,

Columnar self-assembly, electrochemical and luminescence properties of basket-shaped liquid crystalline derivatives of Schiff-base-moulded: P-tert -butyl-calix[4]arene

A new family of supramolecular liquid crystalline compounds with a calix[4]arene core and two linking groups appended on four sides, exhibiting a wide range of hexagonal columnar phases, has been synthesised and well characterised. The liquid crystal beha

Potent human dihydroorotate dehydrogenase inhibitory activity of new quinoline-4-carboxylic acids derived from phenolic aldehydes: Synthesis, cytotoxicity, lipophilicity and molecular docking studies

A series of novel 2-substituted quinoline-4-carboxylic acids was synthesized by Doebner reaction starting from freely available protocatechuic aldehyde and vanillin precursors. Human dihydroorotate dehydrogenase (hDHODH) was recognised as a clear molecular target for these heterocycles. All compounds were also tested for their antiproliferative potential against three cancer cells (MCF-7, A549, A375) and one normal cell line (HaCaT) to evaluate the selective cytotoxicity. Quinoline derivatives 3f and 3g were identified as potent hDHODH inhibitors while 3k and 3l demonstrated high cytotoxic activity against MCF-7 and A375 cells and good selectivity. In addition, the logD7.4 values obtained by the experimental method were found to be in the range from ?1.15 to 1.69. The chemical structures of all compounds were confirmed by IR, NMR and elemental analysis. The compounds pharmacology on the molecular level was revealed by means of molecular docking, highlighting the structural differences that distinguish highly active from medium and low active hDHODH inhibitors.

λ-Shaped mesogens based on chalconyl ester core having variable side chain: Synthesis and characterisation

In present study, we have synthesized two newly chalconyl-ester core LCs having variable side chain and fixed disubstituted butoxy group at another terminal end. All this compounds were well characterized by elemental analysis, FT-IR, 1H NMR. The mesomorphic properties of these compounds were observed by optical polarized light microscopy (POM) and also confirmed by using differential scanning calorimetry (DSC) and X-ray diffraction pattern (XRD). Detailed XRD investigation endorses the presence of the nematic phase in higher angle region and SmC phase in lower angle region. In addition, it is found that all the prepared materials display enantiotropic LCs phases except first four members in series-1 and first member in series-2. Thermal stability of SmC and nematic phase of series-1 is higher as compare to series-2. To get more insights, the DFT based HOMO, LUMO studies are carried out which supports intramolecular charge transfer interactions and stability in this class of mesogens.

Facile bottom-up synthesis of coronene-based 3-fold symmetrical and highly substituted nanographenes from simple aromatics

A facile and efficient self-sorting assemble (CSA) strategy has been paved for bottom-up construction of the 3-fold symmetrical and highly substituted hexa-cata-hexabenzocoronenes (c-HBCs), the trithieno analogues, and larger disc-shaped PAHs from simple

Supergelation via purely aromatic π-π Driven self-assembly of pseudodiscotic oxadiazole mesogens

A series of highly luminescent oxadiazole-based stilbene molecules (OXD4, OXD8, OXD10, and OXD12) exhibiting interesting enantiotropic liquid crystalline and gelation properties have been synthesized and characterized. The molecules possessing longer alkyl substituents, OXD10 and OXD12, possess a pseudodisc shape and are capable of behaving as supergelators in nonpolar solvents, forming self-standing gels with very high thermal and mechanical stability. Notably the self-assembly of these molecules, which do not possess any hydrogen-bonding motifs normally observed in most reported supergelators, is driven purely by π-stacking interactions of the constituent molecules. The d-spacing ratios estimated from XRD analysis of OXD derivatives possessing longer alkyl chains show that the molecules are arranged in a columnar fashion in the mesogens and the self-assembled nanofibers formed in the gelation process.

Synthesis and preliminary biological characterization of new semisynthetic derivatives of ramoplanin

Ramoplanin is a glycolipodepsipeptide antibiotic active against Gram-positive bacteria including vancomycin-resistant enterococci. Ramoplanin inhibits bacterial cell wall biosynthesis by a mechanism different from that of glycopeptides and hence does not show cross-resistance with these antibiotics. The systemic use of ramoplanin has been so far prevented because of its low local tolerability when injected intravenously. To overcome this problem, the fatty acid side chain of ramoplanin was selectively removed and replaced with a variety of different carboxylic acids. Many of the new ramoplanin derivatives showed antimicrobial activity similar to that of the natural precursor coupled with a significantly improved local tolerability. Among them the derivative in which the 2-methylphenylacetic acid has replaced the di-unsaturated fatty acid side chain (48) was selected as the most interesting compound and submitted to further in vitro and in vivo characterization studies.

Electroluminescent liquid crystals

A new class of liquid crystals for use as transport layers and/or emission layers in organic light-emitting diodes has been prepared. Depending on the nature and number of the terminal substituents enatiotropic nematic, smectic and columnar phases are observed. Chain branching gives rise to materials with a low melting point. Several of these liquid crystals electroluminesce in the visible region. The charge transport properties of some of these materials have been evaluated.