68500-41-4 Usage
General Description
4-Hydrazinoquinoline hydrochloride, also known as 4-HQH, is a chemical compound with the molecular formula C9H8N4.HCl. It is an organic compound that is commonly used in pharmaceutical research and as a building block for the synthesis of various heterocyclic compounds. 4-HQH has been studied for its potential anti-cancer and anti-microbial properties, and it is also used in the development of fluorescent sensors and probes for biological imaging. Additionally, it has been investigated for its potential use in the synthesis of various pharmaceuticals and agrochemicals. 4-Hydrazinoquinoline hydrochloride is typically handled with caution due to its potential to cause skin and eye irritation, and it should be stored and used in accordance with proper safety protocols.
Check Digit Verification of cas no
The CAS Registry Mumber 68500-41-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,5,0 and 0 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 68500-41:
(7*6)+(6*8)+(5*5)+(4*0)+(3*0)+(2*4)+(1*1)=124
124 % 10 = 4
So 68500-41-4 is a valid CAS Registry Number.
InChI:InChI=1/C9H9N3.ClH/c10-12-9-5-6-11-8-4-2-1-3-7(8)9;/h1-6H,10H2,(H,11,12);1H
68500-41-4Relevant articles and documents
A new and potent class of quinoline derivatives against cancer
Bispo, Marcelle De L. F.,De Alcantara, Camila C.,De Moraes, Manoel O.,Do ó Pessoa, Cláudia,Rodrigues, Felipe A. R.,Kaiser, Carlos R.,Wardell, Solange M. S. V.,Wardell, James L.,De Souza, Marcus V. N.
, p. 2041 - 2052 (2015)
A new class of 4-quinolinylhydrazone derivatives has been synthesized and evaluated for their cytotoxic potential against three cancer cell lines using the MTT assay. Compounds displaying more than 90 % of growth inhibition were evaluated for in vitro anticancer activities against four human cancer cell lines. The results were expressed as the concentrations that induce 50 % inhibition of cell growth (IC50) in μg/cm3. These compounds exhibited good cytotoxic activity against at least three cancer cell lines, with IC50 values between 0.314 and 4.65 μg/cm3. These derivatives are useful starting points for further study for new anticancer drugs and confirm the potential of quinoline derivatives as lead compounds in anticancer drug discovery. Graphical Abstract: [Figure not available: see fulltext.]
