6853-01-6

Usage

Type of compound

Diketone

Structure

Contains a cyclic five-membered ring with a phenyl group attached at the 2nd position

Uses

a. Intermediate in the synthesis of pharmaceuticals
b. Intermediate in the synthesis of dyes
c. Intermediate in the synthesis of other organic compounds

Application in the food industry

Used as a flavoring agent due to its sweet, fruity odor

Application in chemical reactions

Used in the preparation of chiral ligands for asymmetric hydrogenation reactions

Hazardous properties

a. Flammability
b. Irritating effects on the skin
c. Irritating effects on the eyes

Safety precautions

Proper safety measures should be taken when handling this chemical to minimize risks associated with its hazardous properties

Upstream product

• 65248-41-1 4-Oxo-5-phenylpentansaeure-methylester 
• 936-51-6 2-phenyl-1,3-dioxolane 
• 17082-61-0 1,2-bis(trimethylsiloxy)cyclobutene 
• 1589-82-8 phenylmagnesium bromide 

Relevant academic research and scientific papers

Forging Fluorine-Containing Quaternary Stereocenters by a Light-Driven Organocatalytic Aldol Desymmetrization Process

Reported herein is a light-triggered organocatalytic strategy for the desymmetrization of achiral 2-fluoro-substituted cyclopentane-1,3-diketones. The chemistry is based on an intermolecular aldol reaction of photochemically generated hydroxy-o-quinodimethanes and simultaneously forges two adjacent fully substituted carbon stereocenters, with one bearing a stereogenic carbon–fluorine unit. The method uses readily available substrates, a simple chiral organocatalyst, and mild reaction conditions to afford an array of highly functionalized chiral 2-fluoro-3-hydroxycyclopentanones.

A Convenient Synthesis of Spirodione and 2,2-Disubstituted Cyclopentane-1,3-dione System

An efficient, one pot strategy for the synthesis of spirodione and 2,2-disubstituted cyclopentane-1,3-dione has been developed by using ketals and 1,2-disilyloxycyclobutene in the presence of excess BF3*Et2O.