68535-53-5 Usage
General Description
4-(1H-pyrazol-5-yl)phenol is a chemical compound with the molecular formula C10H8N2O. It is a phenolic compound that is derived from the pyrazole structure, containing a pyrazole ring with a phenyl group attached at the 4-position. 4-(1H-pyrazol-5-yl)phenol has potential applications in pharmaceuticals, as it exhibits biological activities including antioxidant, anti-inflammatory, and antitumor properties. It is also used in the synthesis of various organic compounds and may have potential industrial applications. 4-(1H-pyrazol-5-yl)phenol is a versatile compound with various potential uses in different fields.
Check Digit Verification of cas no
The CAS Registry Mumber 68535-53-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,5,3 and 5 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 68535-53:
(7*6)+(6*8)+(5*5)+(4*3)+(3*5)+(2*5)+(1*3)=155
155 % 10 = 5
So 68535-53-5 is a valid CAS Registry Number.
68535-53-5Relevant articles and documents
Synthesis of aryl-substituted or aryl-fused N-hydroxyethyl and N-hydroxymethypyrazole derivatives as potential ligands for the estrogen receptor
Allahyari-Devin, Maryam,Abedi, Behnam,Navidpour, Latifeh,Shafiee, Abbas
, p. 43 - 53 (2013/02/25)
A new series of N-hydroxyethylpyrazole (12a-f) and N-hydroxymethylpyrazole derivatives (15a-f) were designed for their estrogenic activities, having a 11.0 ± 0.5 A distance between their two hydroxyl groups, aliphatic-OH and phenolic-OH similar to 17β-estradiol (E2) as an endogenous hormone. To synthesize the title compounds, the key intermediate 1,3-dicarbonyl derivatives (2 and 8), were treated with hydrazine hydrate to produce the pyrazole ring 5 and 9. Further hydroxyalkylation of the latter produced the title pyrazoles. The position of hydroxyethyl or hydroxymethyl substituents in the products was determined through 2D NOE NMR spectroscopy.
