68537-05-3

Usage

Chemical structure

1-(but-3-en-1-yloxy)-4-chlorobenzene consists of a benzene ring with a chlorine atom attached to it and a but-3-en-1-yloxy group.

Derivation

Derived from but-3-en-1-ol, a type of alcohol.

Applications

Mainly used in organic synthesis and as a building block in the production of various pharmaceuticals, agrochemicals, and other specialty chemicals.

Potential applications

Has potential applications in the field of materials science and as a precursor to functionalized polymers due to its unique chemical structure.

Safety concerns

It is important to handle this chemical with care, as it may pose risks to human health and the environment.

Upstream product

• 5162-44-7 1-bromo-4-butene 
• 106-48-9 4-chloro-phenol 

Relevant academic research and scientific papers

Gold-Catalyzed 1,2-Diarylation of Alkenes

Herein, we disclose the gold-catalyzed 1,2-diarylation of alkenes through the interplay of ligand-enabled AuI/AuIII catalysis with the idiosyncratic π-activation mode of gold complexes. Unlike the classical migratory-insertion-based approach to 1,2-diarylation, the present approach not only circumvents the formation of direct Ar?Ar′ coupling and Heck-type side products but more intriguingly demonstrates reactivity and selectivity complementary to those of previously known metal catalysis (Pd, Ni, or Cu). Detailed investigations to underpin the mechanistic scenario revealed oxidative addition of aryl iodides to an AuI complex to be the rate-limiting step owing to the non-innocent nature of the aryl alkene.

Application of Bifunctional 2-Amino-1,4-naphthoquinones in Visible-Light-Promoted Photocatalyst-Free Alkene Perfluoroalkyl-Alkenylation

A simple and practical photochemical strategy for intermolecular perfluoroalkyl-alkenylation of alkenes with 2-amino-1,4-naphthoquinones and perfluoroalkyl iodides has been demonstrated under visible-light irradiation. Mechanistic studies reveal that easily available 2-amino-1,4-naphthoquinone substrates can serve as efficient photosensitizers to activate perfluoroalkyl iodides through a photoredox process. Therefore, the developed radical relay reaction proceeds smoothly without additional transition metals and photocatalysts.