685534-25-2Relevant academic research and scientific papers
Novel CCR1 antagonists with oral activity in the mouse collagen induced arthritis
Revesz, Laszlo,Bollbuck, Birgit,Buhl, Thomas,Eder, Joerg,Esser, Ronald,Feifel, Roland,Heng, Richard,Hiestand, Peter,Jachez-Demange, Benedicte,Loetscher, Pius,Sparrer, Helmut,Schlapbach, Achim,Waelchli, Rudolf
, p. 5160 - 5164 (2007/10/03)
Cinnamides as novel CCR1 antagonist chemotypes are described with high affinity to human and rodent receptors. A1B1 and A4B7 showed oral activity in the mouse collagen induced arthritis.
1-(4-BENZYL-PIPERAZIN-1-YL)-3-PHENYL-PROPENONE DERIVATIVES
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Page 35-36, (2010/11/30)
A compound of formula (I), or a pharmaceutically acceptable salt or ester thereof, wherein the symbols have meaning as defined, which are antagonists of CCR-1 and which find use pharmaceutically for treatment of diseases and conditions in which CCR-1 is i
