68578-80-3Relevant academic research and scientific papers
Synthesis of heavily substituted 1,2-amino alcohols in enantiomerically pure form
Garcia-Delgado, Noemi,Reddy, Katamreddy Subba,Sola, Lluis,Riera, Antoni,Pericas, Miquel A.,Verdaguer, Xavier
, p. 7426 - 7428 (2007/10/03)
A simple and convenient methodology for the preparation of optically pure 2-amino-2-aryl-1,1-diphenylethanols is presented. Allylamine was found to produce the ring-opening of triaryloxiranes in a regioselective and a stereospecific fashion. Removal of the allyl protecting group provided the free 1,2-amino alcohols in enantiomerically pure form.
