68621-05-6Relevant academic research and scientific papers
Molecular determinants of ligand binding modes in the histamine H 4 receptor: Linking ligand-based three-dimensional quantitative structure-activity relationship (3D-QSAR) models to in silico guided receptor mutagenesis studies
Istyastono, Enade P.,Nijmeijer, Saskia,Lim, Herman D.,Van De Stolpe, Andrea,Roumen, Luc,Kooistra, Albert J.,Vischer, Henry F.,De Esch, Iwan J. P.,Leurs, Rob,De Graaf, Chris
experimental part, p. 8136 - 8147 (2012/01/05)
The histamine H4 receptor (H4R) is a G protein-coupled receptor (GPCR) that plays an important role in inflammation. Similar to the homologous histamine H3 receptor (H3R), two acidic residues in the H4/sub
