686274-99-7

Upstream product

• 141410-06-2 (S)-indoline-2-carboxylic acid methyl ester 

Downstream Products

• 686275-00-3 1-(diphenyl-phosphinothioyl)-2,3-dihydro-1H-indole-2-carboxylic acid 
• 686275-02-5 (S)-1-(Diphenyl-phosphinothioyl)-2-((R)-4-isopropyl-4,5-dihydro-oxazol-2-yl)-2,3-dihydro-1H-indole 
• 686275-04-7 (S)-1-(Diphenyl-phosphinothioyl)-2-((S)-4-isopropyl-4,5-dihydro-oxazol-2-yl)-2,3-dihydro-1H-indole 
• 686275-03-6 (S)-1-(Diphenyl-phosphinothioyl)-2,3-dihydro-1H-indole-2-carboxylic acid ((S)-1-hydroxymethyl-2-methyl-propyl)-amide 
• 686275-01-4 (S)-1-(Diphenyl-phosphinothioyl)-2,3-dihydro-1H-indole-2-carboxylic acid ((R)-1-hydroxymethyl-2-methyl-propyl)-amide 

Relevant academic research and scientific papers

Chiral aminophosphine-oxazoline auxiliaries applied to copper-catalysed enantioselective 1,4-additions to enones

A series of chiral aminophosphine-oxazoline auxiliaries has been prepared and applied in the copper-catalysed 1,4-addition of diethylzinc to enones. The addition products are obtained quantitatively in up to 67% ee. The most efficient ligand of the series is based on L-indoline carboxylic acid and L-valinol.