6863-75-8

Basic information

• Product Name: 3-AMINO-6-BROMO-1H-PYRAZINE-2-THIONE
• Synonyms: 3-AMINO-6-BROMO-1H-PYRAZINE-2-THIONE;3-AMINO-6-BROMOPYRAZINE-2-THIOL;3-Amino-6-bromo-2(1H)-pyrazinethione
• CAS NO: 6863-75-8
• Molecular Formula: C4H4BrN3S
• Molecular Weight: 206.06
• Mol File: 6863-75-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 3-AMINO-6-BROMO-1H-PYRAZINE-2-THIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-6-BROMO-1H-PYRAZINE-2-THIONE(6863-75-8)
• EPA Substance Registry System: 3-AMINO-6-BROMO-1H-PYRAZINE-2-THIONE(6863-75-8)

Safety Data

• Hazardous Substances Data: 6863-75-8(Hazardous Substances Data)

Usage

General Description

3-Amino-6-bromo-1H-pyrazine-2-thione is a chemical compound with the molecular formula C4H4BrN3S. It is a member of the pyrazine family and contains a thione functional group. 3-AMINO-6-BROMO-1H-PYRAZINE-2-THIONE is commonly used in the synthesis of pharmaceuticals and agrochemicals due to its versatile reactivity and biological activity. It is also a valuable building block for the preparation of heterocyclic compounds and is known for its diverse range of potential applications in the fields of drug discovery and development. Additionally, 3-Amino-6-bromo-1H-pyrazine-2-thione has been researched for its antimicrobial and antiviral properties, making it a potential candidate for the development of new therapeutic agents.

Upstream product

• 24241-18-7 2-amino-3,5-dibromopyrazine 

Downstream Products

• 87444-41-5 6-bromo-2-methylthiazolo<4,5-b>pyrazine 
• 87444-42-6 6-bromo-2-ethoxy-2-methyl-2,3-dihydrothiazolo<4,5-b>pyrazine 
• 87444-38-0 5-bromo-3-(methylthio)pyrazin-2-amine 
• 93497-79-1 6-bromo-2-phenylthiazolo<4,5-b>pyrazine 
• 87444-40-4 6-bromothiazolo<4,5-b>pyrazine 

Relevant articles and documents

Synthesis of tetraaza derivatives of benzoxazinophenothiazine

Tetraaza benzoxazinophenothiazine heterocyclic rings were synthesized and characterized. The key intermediate, 11-amino-6-chlorobenzo[a]-8,10-diazaphenoxazin-5-one was prepared by reaction of 4,5-diamino-6-hydroxypyimidine with 2,3-dichloro-1,4-naphthoquinone in anhydrous sodium carbonate. Whereas the parent tetraaza derivatives: 15-amino-8-bromo-6,9,12,14-tetraazabenzo[a][1,4]benzoxazino[3,2-c] phenothiazine, 9,15-diamino-6,8,12,14-tetraazabenzo[a][1,4]benzoxazino[3,2-c]pheno- thiazine and 15-amino-6,8,12,14-tetraazabenzo[a][1,4]benzoxazino[3,2-c]phenothiazine were synthesized by base catalyzed condensation reactions of 11-amino-6-chlorobenzo[a]-8,10-diazaphenoxazin-5-one with 2-amino-5-bromopyrazin-3-thiol, 4,6-diaminopyrimidine-5-thiol and 4-diaminopyrimidine-5-thiol respectively. The compounds are intensely coloured and are readily reduced with sodium dithionite to their leuco bases which can make them applicable as vat dyes. Their wash fastness, sublimation fastness and staining undyed fabric were evaluated.

USE OF CONDENSED BENZO[B]THIAZINE DERIVATIVES AS CYTOPROTECTANTS

The present invention relates to arylthiazine compounds, metabolites, N-oxides, amides, esters,pharmaceutically acceptable salts, hydrates and solvates thereof and their use as cytoprotectants in the treatment or prophylaxis of diseases or states, either acute or chronic, involving aberrant cellular lipid peroxidation in the central nervous system or in the periphery of the body. The present invention also relates to a method for their preparation and to pharmaceutical composition comprising as an active ingredient one or more of the aforementioned compounds.