87444-41-5 Usage
Uses
Used in Pharmaceutical Industry:
6-Bromo-2-methylthiazolo[5,4-b]pyrazine serves as a crucial building block in the synthesis of various pharmaceuticals. Its unique structure and reactivity allow for the development of new drugs with potential therapeutic applications in the treatment of certain diseases. 6-Bromo-2-methylthiazolo[5,4-b]pyrazine's ability to act as a versatile precursor for the preparation of diverse functionalized compounds contributes to its significance in drug discovery and medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 6-Bromo-2-methylthiazolo[5,4-b]pyrazine is utilized as a key intermediate in the synthesis of pesticides and other agrochemicals. Its potential as a ligand in coordination chemistry enables the creation of novel compounds with improved efficacy and selectivity in controlling pests and diseases in agriculture.
Used in Coordination Chemistry:
6-Bromo-2-methylthiazolo[5,4-b]pyrazine's potential as a ligand in coordination chemistry makes it a valuable component in the design and synthesis of metal complexes. These complexes can exhibit a range of interesting properties, such as catalytic activity, magnetic behavior, or luminescent properties, which can be harnessed in various applications, including catalysis, materials science, and sensing.
Used in Chemical Research and Development:
As a heterocyclic organic compound with unique structural features, 6-Bromo-2-methylthiazolo[5,4-b]pyrazine is an important intermediate in chemical research and development. Its reactivity and versatility allow for the exploration of new synthetic pathways and the creation of novel compounds with potential applications in various fields, such as pharmaceuticals, materials science, and agrochemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 87444-41-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,4,4 and 4 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 87444-41:
(7*8)+(6*7)+(5*4)+(4*4)+(3*4)+(2*4)+(1*1)=155
155 % 10 = 5
So 87444-41-5 is a valid CAS Registry Number.
InChI:InChI=1/C6H4BrN3S/c1-3-9-5-6(11-3)10-4(7)2-8-5/h2H,1H3
87444-41-5Relevant academic research and scientific papers
Knoevenagel Condensation between 2-Methyl-thiazolo[4,5-b]pyrazines and Aldehydes
Sawazaki, Taka,Sohma, Youhei,Kanai, Motomu
, p. 82 - 84 (2022/01/31)
Knoevenagel condensation, an olefin-forming reaction from active methyl/methylene-containing compounds and aldehydes, is a fundamental and useful synthetic method. Benzothiazoles are, however, out of the scope of Knoevenagel condensation. Here, we report that Knoevenagel condensation between aldehydes and 2-methyl-thiazolo[4,5-b]pyrazines (MeTPy), a fused ring structure comprising pyrazine and thiazole, proceeded smoothly, despite minor structural differences from benzothiazoles. This finding will be useful for short synthesis of MeTPy-containing functional molecules, such as a tau probe analog 1.
USE OF CONDENSED BENZO[B]THIAZINE DERIVATIVES AS CYTOPROTECTANTS
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Page/Page column 55, (2014/12/12)
The present invention relates to arylthiazine compounds, metabolites, N-oxides, amides, esters,pharmaceutically acceptable salts, hydrates and solvates thereof and their use as cytoprotectants in the treatment or prophylaxis of diseases or states, either acute or chronic, involving aberrant cellular lipid peroxidation in the central nervous system or in the periphery of the body. The present invention also relates to a method for their preparation and to pharmaceutical composition comprising as an active ingredient one or more of the aforementioned compounds.
