68655-16-3

Upstream product

• 823-45-0 2-(hydroxymethylene)cyclohexanone 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 51933-05-2 (E)-2-(cyclopropylmethylene)cyclohexanone 
• 119-64-2 tetralin 
• 1126-18-7 2-butylcyclohexanone 
• 13388-94-8 spiro[4.5]decan-6-one 
• 85706-68-9 ((E)-2-But-1-enyl)-cyclohex-2-enone 
• 85706-69-0 {6-[1-Cyclopropyl-meth-(E)-ylidene]-cyclohex-1-enyloxy}-trimethyl-silane 
• 410094-58-5 diethyl (2E)-1,1-difluoro-2-(2-oxocyclohexylidene)ethylphosphonate 

Relevant academic research and scientific papers

Synthesis of β-chloro, β-bromo, and β-iodo α,β-unsaturated ketones

A new, efficient method for the preparation of β-chloro, β-bromo, and β-iodo α,β-unsaturated ketones is described.The method involves the reaction of β-diketones or α-hydroxymethylenecycloalkanones with triphenylphosphine dihalides in the presence of trie

5,6-Benzo analogues of prostaglandin E

Disclosed are prostaglandin analogues having the structural formula, STR1 in which: T is selected from the group consisting of carboxyl, alkoxycarbonyl or cyano; M is selected from the group consisting of carbonyl, R-hydroxymethylene or S-hydroxymethylene; L is selected from the group consisting of methylene or methine, provided L is methine only if J is methine; J is selected from the group consisting of methylene, ethylene, R-hydroxymethylene, S-hydroxymethylene or methine, provided J is methine only if L is methine; W is selected from the group consisting of --CH2 --CH-- or trans --CH=C--; T1 and T2 are attached to adjacent carbon atoms; T1 is selected from the group consisting of hydrogen or phenyl, provided T1 is phenyl only if T2 is lower alkyl; T2 is selected from the group consisting of n-pentyl or lower alkyl, provided T2 is lower alkyl only if T1 is phenyl; Or T1 and T2 are joined together to form an alkylene group of 4 or 6 carbon atoms. Also disclosed are methods for preparing such prostaglandin analogues.

5,6-Benzo analogues or prostaglandin E

Disclosed are prostaglandin analogues having the structural formula, STR1 in which: T is selected from the group consisting of carboxyl, alkoxycarbonyl or cyano; M is selected from the group consisting of carbonyl, R-hydroxymethylene or S-hydroxymethylene; L is selected from the group consisting of methylene or methine, provided L is methine only if J is methine; J is selected from the group consisting of methylene, ethylene, R-hydroxymethylene, S-hydroxymethylene or methine, provided J is methine only if L is methine; W is selected from the group consisting of --CH2 --CH-- or trans --CH=C--; T1 and T2 are attached to adjacent carbon atoms; T1 is selected from the group consisting of hydrogen or phenyl, provided T1 is phenyl only if T2 is lower alkyl; T2 is selected from the group consisting of n-pentyl or lower alkyl, provided T2 is lower alkyl only if T1 is phenyl; Or T1 and T2 are joined together to form an alkylene group of 4 or 6 carbon atoms. Also disclosed are methods for preparing such prostaglandin analogues.