686707-06-2

Upstream product

• 150610-45-0 tert-butyl 4-[4-(2-ethoxy-2-oxoacetyl)phenoxy]-1-piperidinecarboxylate 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 
• 70080-54-5 4-hydroxy-alpha-oxobenzeneacetic acid ethyl ester 
• 150610-57-4 ethyl 2-(4-{[1-(tert-butoxycarbonyl)piperidin-4-yl]oxy}phenyl)-3-(7-cyano-2-naphthyl)propanoate 

Relevant academic research and scientific papers

Design, synthesis and biological activity of amidinobicyclic compounds (derivatives of DX-9065a) as factor Xa inhibitors: SAR study of S1 and aryl binding sites

Since factor Xa (fXa) plays a pivotal role in the blood coagulation cascade, inhibition of fXa is thought to be an effective treatment for a variety of thrombotic events. (2S)-2-[4-[[(3S)-1-Acetimidoyl-3-pyrrolidinyl]oxy]phenyl] -3-(7-amidino-2-naphthyl)p