686748-85-6

Upstream product

• 6954-40-1 3-(2-Chlorophenyl)succinic acid 

Downstream Products

• 1239885-31-4 N-[{4-(4-chlorophenyl)-piperazin-1-yl}-methyl]-3-(2-chlorophenyl)-pyrrolidine-2,5-dione 
• 1239885-30-3 N-[{4-(2-chlorophenyl)-piperazin-1-yl}-methyl]-3-(2-chlorophenyl)-pyrrolidine-2,5-dione 
• 1239885-32-5 N-[{4-(3-trifluoromethylphenyl)-piperazin-1-yl}-methyl]-3-(2-chlorophenyl)-pyrrolidine-2,5-dione 

Relevant academic research and scientific papers

Design, synthesis and anticonvulsant properties of new N-Mannich bases derived from 3-phenylpyrrolidine-2,5-diones

The synthesis and anticonvulsant properties of new N-Mannich bases of 3-phenyl- (9a-d), 3-(2-chlorophenyl)- (10a-d), 3-(3-chlorophenyl)- (11a-d) and 3-(4-chlorophenyl)-pyrrolidine-2,5-diones (12a-d) were described. The key synthetic strategies involve the

Synthesis and anticonvulsant properties of new mannich bases derived from 3-aryl-pyrrolidine-2,5-diones. Part 1

A series of new Mannich bases of N-[(4-arylpiperazin-1-yl)-methyl]-3- (chlorophenyl)-pyrrolidine-2,5-diones 10-23 have been synthesized and evaluated for their anticonvulsant activity in maximum electroshock (MES) and subcutaneous pentylenetetrazole (scPT